Evidence map›Paper›PMID 32264892›Full record

ArticleDiagnostic pathology2020

A case of iatrogenic immunodeficiency-associated colonic lymphoma complicating ulcerative colitis.

Kazushi Suzuki, Rintaro Ohe, Takanobu Kabasawa, Naing Ye Aung, Mitsuhiro Yano, Shuichiro Katsumi, Ryo Yanagiya, Masakazu Yamamoto, Tomomi Toubai, Kenichi Ishizawa and 1 more

Open access · goldAbstract readCase Reports
In one paragraph

Article in Diagnostic pathology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Diffuse Large B-cell Lymphoma Developing on the Background of Long-standing Ulcerative Colitis: A Case Report.The Korean journal of gastroenterology = Taehan Sohwagi Hakhoe chi · 2025
    Article
  3. Article
  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Kazushi SuzukiDepartment of Pathological Diagnostics, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan.
Rintaro OheDepartment of Pathological Diagnostics, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan. r-ooe@med.id.yamagata-u.ac.jp.ORCID https://orcid.org/0000-0002-8035-791X
Takanobu KabasawaDepartment of Pathological Diagnostics, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan.ORCID https://orcid.org/0000-0001-7349-3748
Naing Ye AungDepartment of Pathological Diagnostics, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan.ORCID https://orcid.org/0000-0001-5309-781X
Mitsuhiro YanoDepartment of Gastroenterological, General, Breast and Thyroid Surgery (First Department of Surgery), Yamagata University Faculty of Medicine, Yamagata, Japan.
Shuichiro KatsumiDepartment of Gastroenterology, Sanyudo Hospital, Yonezawa, Japan.
Ryo YanagiyaDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Masakazu YamamotoDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Tomomi ToubaiDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Kenichi IshizawaDepartment of Neurology, Hematology, Metabolism, Endocrinology and Diabetology, Yamagata University Faculty of Medicine, Yamagata, Japan.
Mitsunori YamakawaDepartment of Pathological Diagnostics, Yamagata University Faculty of Medicine, 2-2-2 Iida-Nishi, Yamagata, 990-9585, Japan.
Yamagata University · JP

Funding

Japan Society for the Promotion of Science JP17K08736Japan Society for the Promotion of Science JP19K16577
6 · The paper itself

Abstract

backgroundUlcerative colitis (UC) is one of the major types of inflammatory bowel diseases and is associated with a significantly increased risk of not only lymphoproliferative disorders but also lymphomas, of which most cases are related to the long-term usage of immunosuppressants. Here, we demonstrate a very rare case of other iatrogenic immunodeficiency-associated colonic diffuse large B-cell lymphoma (Oii-DLBCL) complicating UC and rectal perforation. In addition, we reviewed the clinicopathological features of previous cases of DLBCL related to UC. CASE PRESENTATION: A 68-year-old man was diagnosed with left-sided UC 26 months prior. Although he was followed by immunosuppressive therapy with azathioprine and infliximab, an emergency total proctocolectomy was performed due to rectal perforation. The resected specimen exhibited irregular wall thickening and elevated multinodular lesions extending from the mid-transverse colon to the rectum, measuring up to 52 cm in length. Histologically, the lesion was diagnosed as Oii-DLBCL and crypt abscess surrounded by mixed inflammatory cell was remained.

conclusionOii-DLBCL complicating UC with rectal perforation is extremely rare. Macro- and microscopic findings are important for early diagnosis of the lesion.

Indexed as

Immunocompromised HostAgedAzathioprineColitis, UlcerativeColorectal NeoplasmsHumansIatrogenic DiseaseImmunosuppressive AgentsInfliximabLymphoma, Large B-Cell, DiffuseMaleAzathioprineImmunosuppressive AgentsInfliximab

Identifiers

PMID32264892
PMCPMC7137478
OpenAlexW3014240922

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.