ArticleBMC endocrine disorders2020
Autoimmune polyglandular syndrome type 2 and autoimmune hepatitis with thymoma-associated myasthenia gravis: case report.
Article in BMC endocrine disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed.
- Diverse clinical manifestations and management strategies in autoimmune polyglandular syndrome: a review of cases.Annals of medicine and surgery (2012) · 2025Review
- Autoimmune thyroid disease and myasthenia gravis: a study bidirectional Mendelian randomization.Frontiers in endocrinology · 2024Article
- Hydrocephalus and myasthenia gravis: neurological manifestations in autoimmune polyendocrine syndrome type II.Acta neurologica Belgica · 2023Article
- First case recognized as autoimmune polyglandular syndrome type 2 with myasthenia gravis in Palestine: A case report and literature review.Annals of medicine and surgery (2012) · 2021Article
- Adrenal crisis and acute exacerbation of interstitial lung disease after thymoma needle biopsy: a case report and literature review.Translational lung cancer research · 2021Article
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Authors and funding
14 authors.
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Abstract
backgroundAutoimmune polyglandular syndrome type 2 (APS-2) is a rare and complex clinical entity, and little is known about its etiology and progression. CASE PRESENTATION: A 52-year-old woman with autoimmune hepatitis (AIH) and bronchial asthma was diagnosed with APS-2; autoimmune Addison's disease (AD), and Hashimoto's thyroiditis (HT), and she underwent prednisolone (PSL) treatment. Five months later, she presented ptosis and was diagnosed with thymoma-associated myasthenia gravis (MG). Thymectomy and PSL treatment with immuno-suppressants appeared to ameliorate MG, AD, AIH, HT, and bronchial asthma. HLA typing analysis revealed that the patient had susceptible HLA alleles to MG, AIH, and HT in a Japanese population.
conclusionsThis case suggests common endocrinological and autoimmune aspects of APS-2 and AIH with thymoma-associated MG, which are considered to be extremely rare complications.
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