Evidence map›Paper›PMID 32260470›Full record

Trial reportBiomolecules2020

Bariatric Surgery Improves HDL Function Examined by ApoA1 Exchange Rate and Cholesterol Efflux Capacity in Patients with Obesity and Type 2 Diabetes.

Shuhui Wang Lorkowski, Gregory Brubaker, Daniel M Rotroff, Sangeeta R Kashyap, Deepak L Bhatt, Steven E Nissen, Philip R Schauer, Ali Aminian, Jonathan D Smith

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Biomolecules, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed, 4 pooled it
6.1field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 4 syntheses or guidelines pooled it, 40 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Pooled it
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Article
  10. HDL Function across the Lifespan: From Childhood, to Pregnancy, to Old Age.International journal of molecular sciences · 2023
    Review
  11. Review
  12. Article
  13. Article
  14. HDL Is Not Dead Yet.Biomedicines · 2022
    Review
  15. Article
  16. Review
  17. Review
  18. Long-Term Weight Loss Strategies for Obesity.The Journal of clinical endocrinology and metabolism · 2021
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Shuhui Wang LorkowskiDepartment of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.
Gregory BrubakerDepartment of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.
Daniel M RotroffDepartment of Quantitative Health Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.ORCID 0000-0003-0553-3220
Sangeeta R KashyapEndocrinology Institute, Cleveland Clinic, Cleveland, OH 44195, USA.
Deepak L BhattBrigham and Women's Hospital Heart and Vascular Center and Harvard Medical School, Boston, MA 02115, USA.
Steven E NissenDepartment of Cardiovascular Medicine, Cleveland Clinic, Cleveland, OH 44195, USA.
Philip R SchauerBariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.
Ali AminianBariatric and Metabolic Institute, Department of General Surgery, Cleveland Clinic, Cleveland, OH 44195, USA.
Jonathan D SmithDepartment of Cardiovascular and Metabolic Sciences, Cleveland Clinic, Cleveland, OH 44195, USA.
Cleveland Clinic · USBrigham and Women's Hospital · US

Funding

Mechanism of ApoA1 Lipidation by ABCA1 in HDL biogenesisR01HL128268 · NHLBI · CLEVELAND CLINIC LERNER COM-CWRU · PI SMITH, JONATHAN D · 2016 to 2023
$3.5M
The Role of PPARγ in Human Placental Development and PreeclampsiaR01HL128628 · NHLBI · WAYNE STATE UNIVERSITY · PI DREWLO, SASCHA · 2015 to 2019
$1.9M
Ethicon Endo-Surgery EES IIS 19900NHLBI NIH HHS R01 HL128268NHLBI NIH HHS R01 HL128628
6 · The paper itself

Abstract

Bariatric surgery improves glycemic control better than medical therapy; however, the effect of bariatric surgery on HDL function is not well characterized. Serum samples were available at baseline, 1-, and 5-years post procedures, for 90 patients with obesity and type 2 diabetes who were randomized to intensive medical therapy (

Indexed as

Bariatric SurgeryApolipoprotein A-ICholesterolDiabetes Mellitus, Type 2FemaleHumansLipoproteins, HDLMaleMiddle AgedObesityTreatment OutcomeApolipoprotein A-ICholesterolLipoproteins, HDLapoA1 exchange ratebariatric surgerycholesterol efflux capacityHDL function

Identifiers

PMID32260470
PMCPMC7226587
OpenAlexW3014265224

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.