Elaboration of Charged Poly(Lactic-co-Glycolic Acid) Microparticles for Effective Release of Tranexamic Acid.

Ming-Hsi Huang, Shun-Ying Huang, Yi-Xuan Chen, Cheng-You Chen, Yung-Sheng Lin

Open access · goldAbstract read

In one paragraph

Article in Polymers, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it

0cells of the map it votes in

1citing papers in PubMed

0.2field-weighted citation impact, top 59% of its field

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 6 citations in OpenAlex.

QbD-based co-loading of paclitaxel and imatinib mesylate by protamine-coated PLGA nanoparticles effective on breast cancer cells.Nanomedicine (London, England) · 2024
Article

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Ming-Hsi HuangNational Institute of Infectious Diseases and Vaccinology, National Health Research Institutes, Miaoli 35053, Taiwan.ORCID 0000-0002-9670-3821

Shun-Ying HuangDepartment of Chemical Engineering, National United University, Miaoli 36063, Taiwan.

Yi-Xuan ChenDepartment of Chemical Engineering, National United University, Miaoli 36063, Taiwan.

Cheng-You ChenPh.D. Program in Materials and Chemical Engineering, National United University, Miaoli 36063, Taiwan.

Yung-Sheng LinDepartment of Chemical Engineering, National United University, Miaoli 36063, Taiwan.ORCID 0000-0002-9522-1812

National United University · TW

Funding

Ministry of Science and Technology, Taiwan 108-2221-E-239-005

6 · The paper itself

Abstract

In this study, tranexamic acid (TA) was used as a model compound to study the charge effect on the physicochemical properties of poly(lactic-co-glycolic acid) (PLGA) microparticles (MPs). Charged PLGA MPs were elaborated by the incorporation of a quaternary ammonium, cetyltrimethylammonium bromide (CTAB), during the double emulsion solvent evaporation process. Three TA-CTAB-carrying modes of PLGA MPs were designed in the CTAB-free (TA-MP), adsorption (TA-CTAB

Indexed as

cetyltrimethylammonium bromidecharge effectcontrolled releasepoly(lactic-co-glycolic acid)tranexamic acid

Identifiers

PMID32260323

DOI10.3390/polym12040808

PMCPMC7240418

OpenAlexW3015145074

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.