Evidence map›Paper›PMID 32260275›Full record

ArticleMetabolites2020

Delta-Integration of Single Gene Shapes the Whole Metabolomic Short-Term Response to Ethanol of Recombinant

Laura Corte, Luca Roscini, Debora Casagrande Pierantoni, Roberto Maria Pellegrino, Carla Emiliani, Marina Basaglia, Lorenzo Favaro, Sergio Casella, Gianluigi Cardinali

Open access · goldAbstract read
In one paragraph

Article in Metabolites, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Review
  3. Integrative Analysis of the Ethanol Tolerance ofInternational journal of molecular sciences · 2023
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Laura CorteDepartment of Pharmaceutical Sciences, University of Perugia, 06121 Perugia, Italy.
Luca RosciniDepartment of Pharmaceutical Sciences, University of Perugia, 06121 Perugia, Italy.ORCID 0000-0003-3706-9936
Debora Casagrande PierantoniDepartment of Pharmaceutical Sciences, University of Perugia, 06121 Perugia, Italy.
Roberto Maria PellegrinoDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06123 Perugia, Italy.
Carla EmilianiDepartment of Chemistry Biology and Biotechnology, University of Perugia, 06123 Perugia, Italy.
Marina BasagliaDepartment of Agronomy Food natural Resources Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro, Italy.
Lorenzo FavaroDepartment of Agronomy Food natural Resources Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro, Italy.ORCID 0000-0002-5650-4422
Sergio CasellaDepartment of Agronomy Food natural Resources Animals and Environment (DAFNAE), University of Padova, 35020 Legnaro, Italy.
Gianluigi CardinaliDepartment of Pharmaceutical Sciences, University of Perugia, 06121 Perugia, Italy.ORCID 0000-0002-4522-7925
University of Perugia · ITUniversity of Padua · IT

Funding

Università degli Studi di Padova DOR1827441/18, DOR1824847/18 and DOR1931153/19.
6 · The paper itself

Abstract

In yeast engineering, metabolic burden is often linked to the reprogramming of resources from regular cellular activities to guarantee recombinant protein(s) production. Therefore, growth parameters can be significantly influenced. Two recombinant strains, previously developed by the multiple δ-integration of a glucoamylase in the industrial

Indexed as

bioethanolConsolidated Bioprocessingethanol stress responseFTIRglucoamylaseindustrial yeast engineeringliquid chromatography-mass spectrometrymetabolic burdenmetabolomicsmultivariate analysis

Identifiers

PMID32260275
PMCPMC7241245
OpenAlexW3014672640

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.