Evidence map›Paper›PMID 32260186›Full record

ArticleViruses2020

Middle East Respiratory Syndrome Coronavirus (MERS-CoV) Seropositive Camel Handlers in Kenya.

Alice N Kiyong'a, Elizabeth A J Cook, Nisreen M A Okba, Velma Kivali, Chantal Reusken, Bart L Haagmans, Eric M Fèvre

Open access · goldAbstract read
In one paragraph

Article in Viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  6. Epidemiological connectivity between humans and animals across an urban landscape.Proceedings of the National Academy of Sciences of the United States of America · 2023
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  14. Evaluation of a real-time RT-PCR panel for detection of SARS-CoV-2 in bat guano.Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2021
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  15. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 3 countries.

Alice N Kiyong'aInternational Livestock Research Institute, Old Naivasha Road, PO Box 30709, Nairobi 00100, Kenya.
Elizabeth A J CookInternational Livestock Research Institute, Old Naivasha Road, PO Box 30709, Nairobi 00100, Kenya.ORCID 0000-0001-6081-8363
Nisreen M A OkbaViroscience Department, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0002-2394-1079
Velma KivaliInternational Livestock Research Institute, Old Naivasha Road, PO Box 30709, Nairobi 00100, Kenya.
Chantal ReuskenViroscience Department, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.
Bart L HaagmansViroscience Department, Erasmus Medical Center, 3015 GD Rotterdam, The Netherlands.ORCID 0000-0001-6221-2015
Eric M FèvreInternational Livestock Research Institute, Old Naivasha Road, PO Box 30709, Nairobi 00100, Kenya.ORCID 0000-0001-8931-4986
International Livestock Research Institute · KEUniversity of Liverpool · GBNational Institute for Public Health and the Environment · NL

Funding

Biotechnology and Biological Sciences Research Council BB/L019019/1Biotechnology and Biological Sciences Research Council (BBSRC) BB/P027954/1
6 · The paper itself

Abstract

Middle East respiratory syndrome (MERS) is a respiratory disease caused by a zoonotic coronavirus (MERS-CoV). Camel handlers, including slaughterhouse workers and herders, are at risk of acquiring MERS-CoV infections. However, there is limited evidence of infections among camel handlers in Africa. The purpose of this study was to determine the presence of antibodies to MERS-CoV in high-risk groups in Kenya. Sera collected from 93 camel handlers, 58 slaughterhouse workers and 35 camel herders, were screened for MERS-CoV antibodies using ELISA and PRNT. We found four seropositive slaughterhouse workers by PRNT. Risk factors amongst the slaughterhouse workers included being the slaughterman (the person who cuts the throat of the camel) and drinking camel blood. Further research is required to understand the epidemiology of MERS-CoV in Africa in relation to occupational risk, with a need for additional studies on the transmission of MERS-CoV from dromedary camels to humans, seroprevalence and associated risk factors.

Indexed as

AbattoirsAdultAnimalsAntibodies, NeutralizingAntibodies, ViralCamelusCoronavirus InfectionsDisease ReservoirsEnzyme-Linked Immunosorbent AssayHumansKenyaMaleMiddle East Respiratory Syndrome CoronavirusOccupational ExposureReverse Transcriptase Polymerase Chain ReactionSeroepidemiologic StudiesAntibodies, NeutralizingAntibodies, ViralcamelscoronavirusRepublic of Kenyaslaughterhouses

Identifiers

PMID32260186
PMCPMC7232417
OpenAlexW3014552539

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.