Evidence map›Paper›PMID 32260167›Full record

ArticleInternational journal of molecular sciences2020

2-Aminopyridine Analogs Inhibit Both Enzymes of the Glyoxylate Shunt in

Alyssa C McVey, Sean Bartlett, Mahmud Kajbaf, Annalisa Pellacani, Viviana Gatta, Päivi Tammela, David R Spring, Martin Welch

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.4field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Review
  3. Study on the phosphorylation of NADJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 3 countries.

Alyssa C McVeyDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK.
Sean BartlettDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.
Mahmud KajbafAptuit LLC, an Evotec Company, 37135 VR Verona, Italy.
Annalisa PellacaniAptuit LLC, an Evotec Company, 37135 VR Verona, Italy.
Viviana GattaDrug Research Program, Division of Pharmaceutical Biosciences, University of Helsinki, FI-00014 Helsinki, Finland.
Päivi TammelaDrug Research Program, Division of Pharmaceutical Biosciences, University of Helsinki, FI-00014 Helsinki, Finland.ORCID 0000-0003-4697-8066
David R SpringDepartment of Chemistry, University of Cambridge, Cambridge CB2 1EW, UK.ORCID 0000-0001-7355-2824
Martin WelchDepartment of Biochemistry, University of Cambridge, Cambridge CB2 1QW, UK.ORCID 0000-0003-3646-1733
University of Cambridge · GBAptuit (Italy) · ITUniversity of Helsinki · FI

Funding

Academy of Finland 277001Biotechnology and Biological Sciences Research Council BB/M019411/1Engineering and Physical Sciences Research Council EP/P020291/1FP7 People: Marie-Curie Actions 642620
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AminopyridinesAnti-Bacterial AgentsBacterial ProteinsCalorimetryCell LineGene Expression Regulation, BacterialGlyoxylatesHumansIsocitrate LyaseMalate SynthaseMolecular StructurePseudomonas aeruginosaalpha-aminopyridineAminopyridinesAnti-Bacterial AgentsBacterial ProteinsGlyoxylatesglyoxylic acidIsocitrate LyaseMalate Synthaseconditionally essential targetenzyme inhibitorglyoxylate shuntisocitrate lyaseisothermal titration calorimetrymalate synthase GPseudomonas aeruginosa

Identifiers

PMID32260167
PMCPMC7177833
OpenAlexW3014614661

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.