Evidence map›Paper›PMID 32260135›Full record

ArticleNutrients2020

Association between Polyphenol Intake and Breast Cancer Risk by Menopausal and Hormone Receptor Status.

Facundo Vitelli-Storelli, Raul Zamora-Ros, Antonio J Molina, Tania Fernández-Villa, Adela Castelló, Juan Pablo Barrio, Pilar Amiano, Eva Ardanaz, Mireia Obón-Santacana, Inés Gómez-Acebo and 13 more

Abstract read
In one paragraph

Article in Nutrients, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors.

Facundo Vitelli-StorelliGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS)/Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.
Raul Zamora-RosUnit of Nutrition and Cancer, Cancer Epidemiology Research Programme, Catalan Institute of Oncology (ICO), Bellvitge Biomedical Research Institute (IDIBELL), L'Hospitalet del Llobregat, 08908 Barcelona, Spain.ORCID 0000-0002-6236-6804
Antonio J MolinaGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS)/Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.
Tania Fernández-VillaGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS)/Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.ORCID 0000-0002-9049-3026
Adela CastellóSchool of Medicine, University of Alcalá, 28871 Alcalá de Henares, Madrid, Spain.
Juan Pablo BarrioGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS)/Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.
Pilar AmianoConsortium for Biomedical Research in Epidemiology &amp.
Eva ArdanazConsortium for Biomedical Research in Epidemiology &amp.
Mireia Obón-SantacanaOncology Data Analytics Program (ODAP), Catalan Institute of Oncology (ICO), L'Hospitalet del Llobregat, 08908 Barcelona, Spain.ORCID 0000-0003-4646-3513
Inés Gómez-AceboConsortium for Biomedical Research in Epidemiology &amp.
Guillermo Fernández-TardónConsortium for Biomedical Research in Epidemiology &amp.
Ana Molina-BarcelóCancer and Public Health Area, FISABIO-Public Health, 46035 Valencia, Spain.ORCID 0000-0001-5113-6475
Juan AlguacilConsortium for Biomedical Research in Epidemiology &amp.ORCID 0000-0003-2703-9725
Rafael Marcos-GrageraConsortium for Biomedical Research in Epidemiology &amp.ORCID 0000-0001-9824-3657
Emma Ruiz-MorenoConsortium for Biomedical Research in Epidemiology &amp.ORCID 0000-0003-3662-4440
Manuela PedrazaDepartment of Oncology, Complejo Asistencial Universitario de León, 24071 León, Spain.
Leire GilConsortium for Biomedical Research in Epidemiology &amp.
Marcela GuevaraConsortium for Biomedical Research in Epidemiology &amp.ORCID 0000-0001-9242-6364
Gemma Castaño-VinyalsConsortium for Biomedical Research in Epidemiology &amp.ORCID 0000-0003-4468-1816
Trinidad Dierssen-SotosConsortium for Biomedical Research in Epidemiology &amp.
Manolis KogevinasConsortium for Biomedical Research in Epidemiology &amp.
Nuria AragonésConsortium for Biomedical Research in Epidemiology &amp.
Vicente MartínGroup of Investigation in Interactions Gene-Environment and Health (GIIGAS)/Institute of Biomedicine (IBIOMED), Universidad de León, 24071 León, Spain.ORCID 0000-0003-0552-2804

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There is limited evidence of phenolic compounds acting as protective agents on several cancer types, including breast cancer (BC). Nevertheless, some polyphenol classes have not been investigated and there is a lack of studies assessing the effect on menopausal status and hormone receptor status as influenced by these compounds. The objective of this study is to evaluate the association between the intake of all polyphenol classes in relation to the BC risk by menopausal and hormone receptor status. We used data from a population-based multi-case-control study (MCC-Spain) including 1472 BC cases and 1577 controls from 12 different regions of Spain. The odds ratios (ORs) with 95% CI were calculated using logistic regression of mixed effects by quartiles and log2 of polyphenol intakes (adjusted for the residual method) of overall BC, menopausal and receptor status. No associations were found between total intake of polyphenols and BC risk. However, inverse associations were found between stilbenes and all BC risk (OR

Indexed as

MenopauseAdultAgedAged, 80 and overBreast NeoplasmsCase-Control StudiesFemaleGene Expression Regulation, NeoplasticHumansLogistic ModelsMiddle AgedOdds RatioPolyphenolsReceptors, EstrogenReceptors, ProgesteroneRisk FactorsPolyphenolsReceptors, EstrogenReceptors, Progesteronebreast cancercase-controlclassesflavonoidsintakepolyphenols

Identifiers

PMID32260135
PMCPMC7231201

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.