Evidence map›Paper›PMID 32260091›Full record

ReviewInternational journal of molecular sciences2020

Antibodies, Nanobodies, or Aptamers-Which Is Best for Deciphering the Proteomes of Non-Model Species?

Poshmaal Dhar, Rasika M Samarasinghe, Sarah Shigdar

Abstract readReview
In one paragraph

Review in International journal of molecular sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Molecular tags for electron cryo-tomography.Emerging topics in life sciences · 2025
    Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Review
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  12. Article
  13. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Poshmaal DharSchool of Medicine, Deakin University, 75 Pigdons Road, Waurn Ponds, Victoria 3216, Australia.
Rasika M SamarasingheSchool of Medicine, Deakin University, 75 Pigdons Road, Waurn Ponds, Victoria 3216, Australia.
Sarah ShigdarSchool of Medicine, Deakin University, 75 Pigdons Road, Waurn Ponds, Victoria 3216, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This planet is home to countless species, some more well-known than the others. While we have developed many techniques to be able to interrogate some of the "omics", proteomics is becoming recognized as a very important part of the puzzle, given how important the protein is as a functional part of the cell. Within human health, the proteome is fairly well-established, with numerous reagents being available to decipher cellular pathways. Recent research advancements have assisted in characterizing the proteomes of some model (non-human) species, however, in many other species, we are only just touching the surface. This review considers three main reagent classes-antibodies, aptamers, and nanobodies-as a means of continuing to investigate the proteomes of non-model species without the complications of understanding the full protein signature of a species. Considerations of ease of production, potential applications, and the necessity for producing a new reagent depending on homology are presented.

Indexed as

AnimalsAntibodiesAptamers, NucleotideHumansProtein BindingProteomeProteomicsSingle-Domain AntibodiesAntibodiesAptamers, NucleotideProteomeSingle-Domain Antibodiesantibodiesaptamersnanobodiesproteinsproteomereagents

Identifiers

PMID32260091
PMCPMC7177290

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.