Evidence map›Paper›PMID 32259493›Full record

ArticleDevelopmental cell2020

Lamin B2, Guardian of Cardiomyocyte Nuclear Division.

Alexander Y Payumo, Guo N Huang

Open access · bronzeAbstract readComment
PubMed Publisher
In one paragraph

Article in Developmental cell, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Alexander Y PayumoCardiovascular Research Institute & Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94158, USA.
Guo N HuangCardiovascular Research Institute & Department of Physiology, University of California, San Francisco, San Francisco, CA 94158, USA; Eli and Edythe Broad Center for Regeneration Medicine and Stem Cell Research, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: guo.huang@ucsf.edu.
University of California, San Francisco · US

Funding

UCSF IRACDA Scholars ProgramK12GM081266 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Raymond M. Esquerra, HOLLY A. INGRAHAM · 2007 to 2026
$19.4M
Molecular control of cardiac regenerative potentialR01HL138456 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Guo Huang · 2018 to 2026
$5.1M
NHLBI NIH HHS R01 HL138456NIGMS NIH HHS K12 GM081266
6 · The paper itself

Abstract

Regenerative capacity is robust in the neonatal mouse heart but is lost during postnatal development when cardiomyocytes undergo cell-cycle arrest and polyploidization. In this issue of Developmental Cell, Han et al. (2020) show that Lamin B2, a nuclear lamina filament supporting cardiomyocyte karyokinesis, also facilitates cell division and cardiac regeneration.

Indexed as

Lamin Type BMyocytes, CardiacAnimalsCell NucleusCell Nucleus DivisionMiceLamin Type B

Identifiers

PMID32259493
OpenAlexW3014259436

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.