Evidence map›Paper›PMID 32259353›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2020

Lipid rafts are required for effective renal D

Andrew C Tiu, Jian Yang, Laureano D Asico, Prasad Konkalmatt, Xiaoxu Zheng, Santiago Cuevas, Xiaoyan Wang, Hewang Lee, Momina Mazhar, Robin A Felder and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 17 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Review
  6. Article
  7. G protein-coupled receptor kinases in hypertension: physiology, pathogenesis, and therapeutic targets.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Review
  8. Article
  9. Article
  10. Review
  11. Dopamine, Immunity, and Disease.Pharmacological reviews · 2023
    Review
  12. Review
  13. Article
  14. Review
  15. Review
  16. Lipid Rafts and Dopamine Receptor Signaling.International journal of molecular sciences · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 2 countries.

Andrew C TiuDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Jian YangDepartment of Clinical Nutrition, The Third Affiliated Hospital of Chongqing Medical University, Chongqing, P.R. China.
Laureano D AsicoDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Prasad KonkalmattDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Xiaoxu ZhengDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Santiago CuevasDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Xiaoyan WangDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Hewang LeeKidney Diseases Branch, National Institute of Diabetes and Digestive and Kidney Diseases, Bethesda, MD, USA.
Momina MazharDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Robin A FelderDepartment of Pathology, University of Virginia School of Medicine, Charlottesville, VA, USA.
Pedro A JoseDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
Van Anthony M VillarDivision of Renal Diseases & Hypertension, Department of Medicine, The George Washington University School of Medicine & Health Sciences, Washington, DC, USA.
George Washington University · USEinstein Medical Center Philadelphia · USFirst Affiliated Hospital of Chongqing Medical University · CNNational Institute of Diabetes and Digestive and Kidney Diseases · USUniversity of Virginia · US

Funding

Spatiotemporal transregulation of D1-like angiotensin receptors in genetically...P01HL074940 · NHLBI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI GILDEA, JOHN JOSEPH · 2004 to 2020
$31.8M
RENAL DOPAMINE-1 RECEPTOR DEFECT IN HYPERTENSIONR01DK039308 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 1987 to 2020
$7.4M
Renal Dopamine Receptor & RegulationR37HL023081 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI JOSE, PEDRO A. · 2007 to 2016
$4.3M
GRK4 & Development of Salt SensitivityR01HL092196 · NHLBI · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES, JOSE, PEDRO A. · 2008 to 2017
$3.6M
Lipid rafts, dopamine 1 receptor, and hypertensionR01DK119652 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI JOSE, PEDRO A. · 2020 to 2023
$2.6M
Role of Dopamine D2 Receptor in Renal Inflammation and InjuryR01DK090918 · NIDDK · UNIVERSITY OF MARYLAND BALTIMORE · PI ARMANDO, INES · 2011 to 2015
$1.7M
Renal G Protein-Coupled Receptor 37L1 Regulates Blood PressureR56DK116828 · NIDDK · GEORGE WASHINGTON UNIVERSITY · PI KONKALMATT, PRASAD · 2018 to 2018
$100k
NHLBI NIH HHS P01 HL074940NHLBI NIH HHS R01 HL092196NHLBI NIH HHS R37 HL023081NIDDK NIH HHS R01 DK039308NIDDK NIH HHS R01 DK090918NIDDK NIH HHS R01 DK119652NIDDK NIH HHS R56 DK116828NIH HHS KY19024
6 · The paper itself

Abstract

Effective receptor signaling is anchored on the preferential localization of the receptor in lipid rafts, which are plasma membrane platforms replete with cholesterol and sphingolipids. We hypothesized that the dopamine D

Indexed as

AnimalsBinding SitesBlood PressureCells, CulturedCyclic AMPGene SilencingHumansKidneyKidney Tubules, ProximalLipoylationMaleMembrane MicrodomainsMiceMice, Inbred C57BLMutagenesis, Site-DirectedOxidative StressCyclic AMPDRD1 protein, humanDrd1 protein, mouseReceptors, Dopamine D1Sodiumblood pressureCRAC motifdopamine receptorsgene rescuelipid raftpalmitoylationsorting nexin 19 (SNX19)

Identifiers

PMID32259353
PMCPMC7200283
OpenAlexW3014827666

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.