Evidence map›Paper›PMID 32259342›Full record

ReviewClinical cardiology2020

Interpretation of T-wave inversion in physiological and pathological conditions: Current state and future perspectives.

Flavio D'Ascenzi, Francesca Anselmi, Paolo Emilio Adami, Antonio Pelliccia

Open access · goldAbstract readReview
In one paragraph

Review in Clinical cardiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed, 1 pooled it
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 1 synthesis or guideline pooled it, 55 citations in OpenAlex.

  1. Guideline
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Prevalence and prognosis of structural heart disease among athletes with negative T waves and normal transthoracic echocardiography.Clinical research in cardiology : official journal of the German Cardiac Society · 2024
    Article
  8. Review
  9. Review
  10. Article
  11. Athlete ECG T-wave abnormality interpretation patterns by non-experts.American heart journal plus : cardiology research and practice · 2022
    Article
  12. Article
  13. Article
  14. T-wave inversion as a manifestation of COVID-19 infection: a case series.Journal of interventional cardiac electrophysiology : an international journal of arrhythmias and pacing · 2020
    Observational
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 2 countries.

Flavio D'AscenziDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.ORCID https://orcid.org/0000-0002-0947-6836
Francesca AnselmiDepartment of Medical Biotechnologies, Division of Cardiology, University of Siena, Siena, Italy.
Paolo Emilio AdamiHealth and Science Department, World Athletics, Monaco, Monaco.
Antonio PellicciaInstitute of Sports Medicine and Science, Rome, Italy.
University of Siena · ITInternational University of Monaco · MC

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The presence of T-wave inversion (TWI) at 12-lead electrocardiogram (ECG) in competitive athletes is one of the major diagnostic challenges for sports physicians and consulting cardiologists. Indeed, while the presence of TWI may be associated with some benign conditions and it may be occasionally seen in healthy athletes presenting signs of cardiac remodeling, it may also represent an early sign of an underlying, concealed structural heart disease or life-threatening arrhythmogenic cardiomyopathies, which may be responsible for exercise-related sudden cardiac death (SCD). The interpretation of TWI in athletes is complex and the inherent implications for the clinical practice represent a conundrum for physicians. Accordingly, the detection of TWI should be viewed as a potential red flag on the ECG of young and apparently healthy athletes and warrants further investigations because it may represent the initial expression of cardiomyopathies that may not be evident until many years later and that may ultimately be associated with adverse outcomes. The aim of this review is, therefore, to report an update of the literature on TWI in athletes, with a specific focus on the interpretation and management.

Indexed as

ElectrocardiographyArrhythmias, CardiacCardiomyopathiesExerciseHumansSportsathletesathlete's heartcardiomyopathydeathelectrocardiographynegative T-wavessports cardiologysudden cardiac

Identifiers

PMID32259342
PMCPMC7403675
OpenAlexW3014318198

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.