Evidence map›Paper›PMID 32259146›Full record

ArticleTurkish journal of anaesthesiology and reanimation2020

The Effect of Tranexamic Acid Administration on Perioperative Bleeding in Patients Undergoing Knee or Hip Arthroplasty: A Single-Centre Retrospective Study.

Akira Nemoto, Kana Mizuno, Toru Goyagi

Abstract read
In one paragraph

Article in Turkish journal of anaesthesiology and reanimation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Akira NemotoDepartment of Anaesthesia and Intensive Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.ORCID https://orcid.org/0000-0003-2685-7494
Kana MizunoDepartment of Anaesthesia and Intensive Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.ORCID https://orcid.org/0000-0001-8151-1766
Toru GoyagiDepartment of Anaesthesia and Intensive Care Medicine, Akita University Graduate School of Medicine, Akita, Japan.ORCID https://orcid.org/0000-0002-3077-4790

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTranexamic acid (TXA) has been used to reduce perioperative bleeding in various surgeries because of its antifibrinolytic effect. Recently, patients undergoing orthopaedic surgery in our institution received a loading dose of TXA (10 00 mg) before surgery, followed by 100 mg h

methodsA retrospective cross-sectional study was conducted for the records in patients who underwent surgery without TXA administration (control group) and patients who underwent surgery with TXA administration (TXA group). Amount of intraoperative blood loss, intraoperative infusion volume, intraoperative blood transfusion volume, postoperative blood transfusion volume, changes in haemoglobin concentrations (ΔHb) and estimated blood loss were collected. Data were adjusted by propensity score method.

resultsA total of 126 (63 in the control group and 63 in the TXA group) patients were included during the study period. Intraoperative infusion, postoperative transfusion, ΔHb and estimated blood loss were significantly reduced in the TXA group, although there were no significant differences in the volumes of intraoperative transfusion and blood loss.

conclusionThe administration of TXA (loading dose of 1000 mg and continuous infusion of 100 mg h

Indexed as

Arthroplastytranexamic acidtransfusion

Identifiers

PMID32259146
PMCPMC7101183

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.