Evidence map›Paper›PMID 32259109›Full record

ArticleCritical care explorations2020

Isoflurane Sedation in Patients Undergoing Venoarterial Extracorporeal Membrane Oxygenation Treatment for Cardiogenic Shock-An Observational Propensity-Matched Study.

Clemens Scherer, Danny Kupka, Thomas J Stocker, Dominik Joskowiak, Hanna Scheuplein, Carmen Maria Schönegger, Frank Born, Christopher Stremmel, Enzo Lüsebrink, Konstantin Stark and 7 more

Open access · goldAbstract read
In one paragraph

Article in Critical care explorations, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

  1. Trial
  2. Review
  3. Review
  4. Review
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 1 institution in 1 country.

Clemens SchererIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Danny KupkaIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Thomas J StockerIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Dominik JoskowiakDepartment of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
Hanna ScheupleinIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Carmen Maria SchöneggerIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Frank BornDepartment of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
Christopher StremmelIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Enzo LüsebrinkIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Konstantin StarkIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Mathias OrbanIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Tobias PetzoldIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Sven PeterssDepartment of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
Jörg HausleiterIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Christian HaglDepartment of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
Steffen MassbergIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
Martin OrbanIntensive Care Unit and Department of Cardiology, University Hospital, LMU Munich, Munich, Germany.
LMU Klinikum · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The feasibility and hemodynamic effects of isoflurane sedation in cardiogenic shock in the presence of venoarterial extracorporeal membrane oxygenation treatment are currently unknown.

designRetrospective single-center study.

settingCardiac ICU of Munich university hospital. PATIENTS/SUBJECTS: Cardiogenic shock patients with venoarterial extracorporeal membrane oxygenation treatment under sedation with volatile isoflurane between November 2018 and October 2019 have been enrolled in this study and were matched by propensity score in a 1:1 ratio with IV sedated patients treated between January 2013 and November 2018 from the cardiogenic shock registry of the university hospital of Munich. MEASUREMENTS AND MAIN

resultsIsoflurane sedation was used in 32 patients with cardiogenic shock and venoarterial extracorporeal membrane oxygenation treatment. The mean age of conventionally sedated patients was 58.4 ± 13.8 years and 56.3 ± 11.5 years for patients with isoflurane sedation (

conclusionsVolatile sedation with isoflurane is feasible-albeit at higher costs-in patients with cardiogenic shock and venoarterial extracorporeal membrane oxygenation treatment and was not associated with higher catecholamine dosage or extracorporeal membrane oxygenation flow rate compared with IV sedation.

Indexed as

cardiac arrestcardiogenic shockextracorporeal membrane oxygenationhypnotics and sedativesisofluraneresuscitation

Identifiers

PMID32259109
PMCPMC7098543
OpenAlexW3011862158

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.