Evidence map›Paper›PMID 32258899›Full record

ArticleACS omega2020

Synthesis of Inorganic Pyrophosphatase-Nanodiamond Conjugates Resistant to Calcium and Fluoride.

Anastasiya V Valueva, Roman S Romanov, Nataliya N Vorobyeva, Svetlana A Kurilova, Elena V Rodina

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. HParasitology research · 2024
    Review
  2. Thermophilic Inorganic Pyrophosphatase Ton1914 fromInternational journal of molecular sciences · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Anastasiya V ValuevaPharmaceutical Department, Pavlov Ryazan State Medical University, 9 Vysokovol'tnaya Street, Ryazan 390026, Russia.
Roman S RomanovDepartment of Fundamental Medicine, Lomonosov Moscow State University, 31, Build. 5, Lomonosovsky Prospect, Moscow 119991, Russia.
Nataliya N VorobyevaChemistry Department, Lomonosov Moscow State University, 1, Build. 3, Leninskie Gory, Moscow 119992, Russia.
Svetlana A KurilovaA.N. Belozersky Institute of Physico-Chemical Biology, Lomonosov Moscow State University, 1, Build. 40, Leninskie Gory, Moscow 119992, Russia.
Elena V RodinaChemistry Department, Lomonosov Moscow State University, 1, Build. 3, Leninskie Gory, Moscow 119992, Russia.
Lomonosov Moscow State University · RURyazan State Medical University named after Academician I.P. Pavlov · RU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pyrophosphate arthropathy is the mineralization defect in humans caused by the deposition of microcrystals of calcium pyrophosphate dihydrate in joint tissues. As a potential therapeutic strategy for the treatment of pyrophosphate arthropathy, delivery of exogenous pyrophosphate-hydrolyzing enzymes, inorganic pyrophosphatases (PPases), to the synovial fluid has been suggested. Previously, we synthesized the conjugates of

Identifiers

PMID32258899
PMCPMC7114608
OpenAlexW3012040865

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.