ArticleACS omega2020
Evaluating Protein Engineering Thermostability Prediction Tools Using an Independently Generated Dataset.
Article in ACS omega, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 33 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
33 citing papers in PubMed.
- Collective Variable-Guided Engineering of the Free-Energy Surface of a Small Peptide.Journal of chemical information and modeling · 2026Article
- Thermostability Engineering in Therapeutic Antioxidant Enzymes: From Molecular Fundamentals to Oxidative Stress Applications.International journal of molecular sciences · 2026Review
- StabLyzeGraph: High-throughput screening of combinatorial mutations using graph neural networks.Protein science : a publication of the Protein Society · 2026Article
- Protein folding stability estimation with explicit consideration of unfolded states.Nature communications · 2026Article
- ProGraphTrans: multimodal dynamic collaborative framework for protein representation learning.BMC biology · 2025Article
- Modifying the potato tuber storage protein patatin targeting improved thermal stability.Planta · 2025Article
- Enzyme-Embedded Biodegradable Plastic for Sustainable Applications: Advances, Challenges, and Perspectives.ACS applied bio materials · 2025Review
- Prediction of mutation-induced protein stability changes based on the geometric representations learned by a self-supervised method.BMC bioinformatics · 2024Article
- Protein stability prediction by fine-tuning a protein language model on a mega-scale dataset.PLoS computational biology · 2024Article
- A Novel Non-Destructive Rapid Tool for Estimating Amino Acid Composition and Secondary Structures of Proteins in Solution.Small methods · 2024Article
- Enabling high-throughput enzyme discovery and engineering with a low-cost, robot-assisted pipeline.Scientific reports · 2024Article
- AI-Driven Spectral Decomposition: Predicting the Most Probable Protein Compositions from Surface Enhanced Raman Spectroscopy Spectra of Amino Acids.Bioengineering (Basel, Switzerland) · 2024Article
- High-Temperature Tolerance Protein Engineering through Deep Evolution.Biodesign research · 2024Article
- Prediction of Enzyme Catalysis by Computing Reaction Energy Barriers via Steered QM/MM Molecular Dynamics Simulations and Machine Learning.Journal of chemical information and modeling · 2023Article
- Understanding the Stabilization Mechanism of a Thermostable Mutant of Hygromycin B Phosphotransferase by Protein Sector-Guided Dynamic Analysis.ACS omega · 2023Article
- A FRET-Based Assay for the Identification of PCNA Inhibitors.International journal of molecular sciences · 2023Article
- Recent Advances in β-Glucosidase Sequence and Structure Engineering: A Brief Review.Molecules (Basel, Switzerland) · 2023Review
- Accurate Prediction of Enzyme Thermostabilization with Rosetta Using AlphaFold Ensembles.Journal of chemical information and modeling · 2023Article
- Protein conformation stabilized by newly formed turns for thermal resilience.Biophysical journal · 2023Article
- The role of data imbalance bias in the prediction of protein stability change upon mutation.PloS one · 2023Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Engineering proteins to enhance thermal stability is a widely utilized approach for creating industrially relevant biocatalysts. The development of new experimental datasets and computational tools to guide these engineering efforts remains an active area of research. Thus, to complement the previously reported measures of
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.