Evidence map›Paper›PMID 32258429›Full record

ArticleNPJ digital medicine2020

Machine intelligence in healthcare-perspectives on trustworthiness, explainability, usability, and transparency.

Christine M Cutillo, Karlie R Sharma, Luca Foschini, Shinjini Kundu, Maxine Mackintosh, Kenneth D Mandl, MI in Healthcare Workshop Working Group

Abstract read
In one paragraph

Article in NPJ digital medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 124 papers, 6 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
124citing papers in PubMed, 6 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

124 citing papers in PubMed, 6 syntheses or guidelines pooled it.

  1. Pooled it
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  15. The evolution of AI-integrated genome editing and its challenges.Mammalian genome : official journal of the International Mammalian Genome Society · 2026
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64 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Christine M Cutillo *1National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD USA.
Karlie R Sharma *1National Center for Advancing Translational Sciences, National Institutes of Health, Bethesda, MD USA.ORCID 0000-0003-3435-7721
Luca Foschini2Evidation Health Inc., San Mateo, CA USA.ORCID 0000-0003-1409-3570
Shinjini Kundu3Department of Radiology, The Johns Hopkins Hospital, Baltimore, MD USA.
Maxine Mackintosh4University College London, London, UK.
Kenneth D Mandl6Computational Health Informatics Program, Boston Children's Hospital, Boston, MA USA.
MI in Healthcare Workshop Working Group

Funding

NCATS Biomedical Data Translator ProgramZIATR000276 · NCATS · NATIONAL CENTER FOR ADVANCING TRANSLATIONAL SCIENCES · PI MATHÉ, EWY · 2017 to 2025
$6.3M
6 · The paper itself

Abstract

Machine Intelligence (MI) is rapidly becoming an important approach across biomedical discovery, clinical research, medical diagnostics/devices, and precision medicine. Such tools can uncover new possibilities for researchers, physicians, and patients, allowing them to make more informed decisions and achieve better outcomes. When deployed in healthcare settings, these approaches have the potential to enhance efficiency and effectiveness of the health research and care ecosystem, and ultimately improve quality of patient care. In response to the increased use of MI in healthcare, and issues associated when applying such approaches to clinical care settings, the National Institutes of Health (NIH) and National Center for Advancing Translational Sciences (NCATS) co-hosted a Machine Intelligence in Healthcare workshop with the National Cancer Institute (NCI) and the National Institute of Biomedical Imaging and Bioengineering (NIBIB) on 12 July 2019. Speakers and attendees included researchers, clinicians and patients/ patient advocates, with representation from industry, academia, and federal agencies. A number of issues were addressed, including: data quality and quantity; access and use of electronic health records (EHRs); transparency and explainability of the system in contrast to the entire clinical workflow; and the impact of bias on system outputs, among other topics. This whitepaper reports on key issues associated with MI specific to applications in the healthcare field, identifies areas of improvement for MI systems in the context of healthcare, and proposes avenues and solutions for these issues, with the aim of surfacing key areas that, if appropriately addressed, could accelerate progress in the field effectively, transparently, and ethically.

Indexed as

DiagnosisDisease preventionMedical imagingPublic healthTherapeutics

Identifiers

PMID32258429
PMCPMC7099019

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.