Evidence map›Paper›PMID 32258205›Full record

ArticleOpen forum infectious diseases2020

Getting Personal: How Childhood Vaccination Policies Shape the Landscape of Vaccine Exemptions.

Romain Garnier, Emma R Nedell, Saad B Omer, Shweta Bansal

Abstract read
In one paragraph

Article in Open forum infectious diseases, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Romain GarnierDepartment of Biology, Georgetown University, Washington, District of Columbia, USA.ORCID 0000-0002-6583-3527
Emma R NedellDepartment of Biology, Georgetown University, Washington, District of Columbia, USA.
Saad B OmerYale Institute for Global Health, Yale University, New Haven, Conneticut, USA.
Shweta BansalDepartment of Biology, Georgetown University, Washington, District of Columbia, USA.

Funding

Vaccine hesitancy and erosion of herd immunity: harnessing big data to forecast disease re-emergenceR01GM123007 · NIGMS · GEORGETOWN UNIVERSITY · PI BANSAL, SHWETA · 2017 to 2021
$2.1M
6 · The paper itself

Abstract

backgroundState-mandated school entry immunization requirements in the United States play an important role in achieving high vaccine coverage, but variations in vaccine exemption policies result in a patchwork of vaccine coverage across the country.

methodsIn this study, we evaluate epidemiological effects and spatial variations in nonmedical exemption (NME) rates in the context of vaccine policies. We first analyze the correlation between NME rates and vaccine coverage for 3 significant childhood vaccinations. Furthermore, we assess the effects of policy changes in a subset of states, using a correlative approach at the state level and performing a clustering analysis at the county level.

resultsWe find that higher rates of exemptions are associated with lower vaccination rates of school-aged children in all cases. In a subset of states where exemption policy has recently changed, we show that the effects on statewide NME rates vary widely and that decreases in NMEs can lead to an increase in other types of exemptions. Finally, our clustering analysis in California, Illinois, and Connecticut shows that policy changes affect the spatial distribution of NMEs.

conclusionsOur work suggests that vaccination policies have significant impacts on patterns of herd immunity. Our findings can be used to develop evidence-based vaccine legislation.

Indexed as

disease ecologyherd immunityimmunization

Identifiers

PMID32258205
PMCPMC7111605

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.