Evidence map›Paper›PMID 32258052›Full record

ArticleSkin appendage disorders2020

Treatment of Male-Pattern Alopecia with Platelet-Rich Plasma.

Aline Lissa Okita, Denise Steiner, Sineida Berbert Ferreira, Paulo Müller Ramos, Walter Ferreira, Rebecca Silveira, Maria Luiza Mussi, Rafael Eliahu Vaidergorn, Rachel Berbert Ferreira

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Skin appendage disorders, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 8 citations in OpenAlex.

  1. Pooled it
  2. Injections of platelet-rich plasma prepared by automatic blood cell separator combined with topical 5% minoxidil in the treatment of male androgenetic alopecia.Skin research and technology : official journal of International Society for Bioengineering and the Skin (ISBS) [and] International Society for Digital Imaging of Skin (ISDIS) [and] International Society for Skin Imaging (ISSI) · 2023
    Trial
  3. Review
  4. [Platelet-rich plasma (PRP) for the treatment of androgenetic alopecia (AGA): a review of the current literature].Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete · 2022
    Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Aline Lissa OkitaDepartamento de Dermatologia da Universidade de Mogi das Cruzes, São Paulo, Brazil.
Denise SteinerDepartamento de Dermatologia da Universidade de Mogi das Cruzes, São Paulo, Brazil.
Sineida Berbert FerreiraCentro Paranaense de Estudos em Dermatologia, São Paulo, Brazil.
Paulo Müller RamosCentro Paranaense de Estudos em Dermatologia, São Paulo, Brazil.
Walter FerreiraCentro Paranaense de Estudos em Dermatologia, São Paulo, Brazil.
Rebecca SilveiraDepartamento de Dermatologia da Universidade de Mogi das Cruzes, São Paulo, Brazil.
Maria Luiza MussiDepartamento de Dermatologia da Universidade de Mogi das Cruzes, São Paulo, Brazil.
Rafael Eliahu VaidergornDepartamento de Dermatologia da Universidade de Mogi das Cruzes, São Paulo, Brazil.
Rachel Berbert FerreiraCentro Paranaense de Estudos em Dermatologia, São Paulo, Brazil.
Universidade de Mogi das Cruzes · BRCentro Brasileiro de Estudos em Dermatologia · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAndrogenetic alopecia (AGA) affects up to 80% of men and 50% of women throughout their lifetime, causing significant discomfort. Minoxidil, finasteride, and low-level laser light therapy are the only Food and Drug Administration-approved treatments for AGA, and they have shown positive results in randomized controlled trials and meta-analyses. However, their efficacy is limited, and new therapies are needed. Injection of platelet-rich plasma (PRP), a minimally invasive technique, has been described by several authors as a promising treatment for AGA. Although many studies report beneficial effects of PRP on AGA, there is no standardized practice for PRP preparation and administration or a standard method to evaluate results.

objectiveThe aim of this study was to evaluate the efficacy of manually prepared PRP in the treatment of male AGA. MATERIALS AND

methodsWe treated 20 male patients with AGA with 3 monthly injections of PRP and analyzed results by TrichoScan®.

resultsIn this study, there was no statistically significant improvement in hair count or proportion of anagen hairs.

conclusionsThis lack of response could be related to any of the variables during PRP preparation described above and also to the limited number of patients in the study.

Indexed as

AlopeciaAndrogenetic alopeciaBaldnessHair disorderPlatelet-rich plasma

Identifiers

PMID32258052
PMCPMC7109383
OpenAlexW2995923551

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.