Evidence map›Paper›PMID 32258047›Full record

ReviewFrontiers in nutrition2020

Recent Progress and Recommendations on Celiac Disease From the Working Group on Prolamin Analysis and Toxicity.

Katharina A Scherf, Carlo Catassi, Fernando Chirdo, Paul J Ciclitira, Conleth Feighery, Carmen Gianfrani, Frits Koning, Knut E A Lundin, Detlef Schuppan, Marinus J M Smulders and 3 more

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in nutrition, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 53 citations in OpenAlex.

  1. Article
  2. Probiotics: a supplement to the gluten-free diet in celiac disease.Gastroenterology and hepatology from bed to bench · 2025
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  10. The global burden of coeliac disease: opportunities and challenges.Nature reviews. Gastroenterology & hepatology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 13 institutions in 9 countries.

Katharina A ScherfDepartment of Bioactive and Functional Food Chemistry, Institute of Applied Biosciences, Karlsruhe Institute of Technology (KIT), Karlsruhe, Germany.
Carlo CatassiDepartment of Pediatrics, Polytechnic University of Marche, Ancona, Italy.
Fernando ChirdoInstituto de Estudios Inmunologicos y Fisiopatologicos- IIFP (UNLP-CONICET), Universidad Nacional de La Plata, La Plata, Argentina.
Paul J CiclitiraNorwich Medical School, University of East Anglia, Norwich, United Kingdom.
Conleth FeigherySt. James's Hospital, University of Dublin, Dublin, Ireland.
Carmen GianfraniInstitute of Biochemistry and Cell Biology, Italian National Council of Research, Naples, Italy.
Frits KoningLeiden University Medical Centre, Leiden, Netherlands.
Knut E A LundinDepartment of Gastroenterology, Oslo University Hospital Rikshospitalet and Stiftelsen KG Jebsen Coeliac Disease Research Centre, University of Oslo, Oslo, Norway.
Detlef SchuppanInstitute for Translational Medicine, University Medical Center of the Johannes Gutenberg University Mainz, Mainz, Germany.
Marinus J M SmuldersPlant Breeding, Wageningen University & Research, Wageningen, Netherlands.
Olivier TranquetINRAE, UR BIA, Nantes, France.
Riccardo TronconeEuropean Laboratory for the Investigation of Food Induced Diseases (ELFID), Department of Medical Translational Sciences, University Federico II, Naples, Italy.
Peter Koehlerbiotask AG, Esslingen, Germany.
Biopolymères Interactions Assemblages · FRFederico II University Hospital · ITKarlsruhe Institute of Technology · DEKlinikum Esslingen · DELeiden University Medical Center · NLMarche Polytechnic University · ITNational Research Council · ITOslo University Hospital · NOSt. James's Hospital · IEUniversidad Nacional de La Plata · ARUniversity Medical Center of the Johannes Gutenberg University Mainz · DEUniversity of East Anglia · GBWageningen University & Research · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Celiac disease (CD) affects a growing number of individuals worldwide. To elucidate the causes for this increase, future multidisciplinary collaboration is key to understanding the interactions between immunoreactive components in gluten-containing cereals and the human gastrointestinal tract and immune system and to devise strategies for CD prevention and treatment beyond the gluten-free diet. During the last meetings, the Working Group on Prolamin Analysis and Toxicity (Prolamin Working Group, PWG) discussed recent progress in the field together with key stakeholders from celiac disease societies, academia, industry and regulatory bodies. Based on the current state of knowledge, this perspective from the PWG members provides recommendations regarding clinical, analytical and legal aspects of CD. The selected key topics that require future multidisciplinary collaborative efforts in the clinical field are to collect robust data on the increasing prevalence of CD, to evaluate what is special about gluten-specific T cells, to study their kinetics and transcriptomics and to put some attention to the identification of the environmental agents that facilitate the breaking of tolerance to gluten. In the field of gluten analysis, the key topics are the precise assessment of gluten immunoreactive components in wheat, rye and barley to understand how these are affected by genetic and environmental factors, the comparison of different methods for compliance monitoring of gluten-free products and the development of improved reference materials for gluten analysis.

Indexed as

barleyceliac diseaseglutengluten-free dietProlamin Working Groupryewheat

Identifiers

PMID32258047
PMCPMC7090026
OpenAlexW3011193195

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.