Evidence map›Paper›PMID 32258041›Full record

ReviewFrontiers in cell and developmental biology2020

Evolution and Developmental System Drift in the Endoderm Gene Regulatory Network of

Chee Kiang Ewe, Yamila N Torres Cleuren, Joel H Rothman

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in cell and developmental biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. The GRN concept as a guide for evolutionary developmental biology.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2023
    Article
  5. Article
  6. A synthetic synthesis to explore animal evolution and development.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Review
  7. Article
  8. Article
  9. Review
  10. Natural cryptic variation in epigenetic modulation of an embryonic gene regulatory network.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 2 countries.

Chee Kiang EweDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, United States.
Yamila N Torres CleurenComputational Biology Unit, Department of Informatics, University of Bergen, Bergen, Norway.
Joel H RothmanDepartment of Molecular, Cellular, and Developmental Biology, University of California, Santa Barbara, Santa Barbara, CA, United States.
University of California, Santa Barbara · USUniversity of Bergen · NO

Funding

Developmental reprogramming and transorganogenesisR01HD081266 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI Joel H. Rothman · 2015 to 2026
$3.0M
Plasticity in an embryonic gene regulatory networkR01HD082347 · NICHD · UNIVERSITY OF CALIFORNIA SANTA BARBARA · PI ROTHMAN, JOEL H. · 2015 to 2019
$1.5M
NICHD NIH HHS R01 HD081266NICHD NIH HHS R01 HD082347
6 · The paper itself

Abstract

Developmental gene regulatory networks (GRNs) underpin metazoan embryogenesis and have undergone substantial modification to generate the tremendous variety of animal forms present on Earth today. The nematode

Indexed as

Caenorhabditisdevelopmental hourglassdevelopmental system driftplasticityrobustness

Identifiers

PMID32258041
PMCPMC7093329
OpenAlexW3012183202

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.