Evidence map›Paper›PMID 32258012›Full record

ArticleFrontiers in bioengineering and biotechnology2020

In Preparation for Outdoor Pharming: Griffithsin Can Be Expressed in

Paul Eapen, Jennifer Cates, Rich Mundell, Kenneth E Palmer, Joshua L Fuqua

Abstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Paul EapenUniversity of Louisville School of Medicine, University of Louisville, Louisville, KY, United States.
Jennifer CatesUniversity of Louisville School of Medicine, University of Louisville, Louisville, KY, United States.
Rich MundellUniversity of Kentucky College of Agriculture, Food and Environment, University of Kentucky, Lexington, KY, United States.
Kenneth E PalmerUniversity of Louisville School of Medicine, University of Louisville, Louisville, KY, United States.
Joshua L FuquaUniversity of Louisville School of Medicine, University of Louisville, Louisville, KY, United States.

Funding

Project 3: PREVENT: A first-in-human clinical trial of Griffithsin, an HIV entryU19AI113182 · NIAID · UNIVERSITY OF LOUISVILLE · PI BRAND, RHONDA METTER · 2014 to 2018
$14.8M
NIAID NIH HHS U19 AI113182
6 · The paper itself

Abstract

Griffithsin is an algae-derived lectin with strong anti-viral activity against HIV and a positive safety profile. Multiple clinical studies are investigating griffithsin's utility as topical HIV microbicide. HIV microbicides are an extremely cost-sensitive market and plant-based griffithsin protein expression has the potential to meet those demands. The griffithsin product used in the clinic has been expressed and purified in

Indexed as

antiviralensilegriffithsinmicrobicideN. excelsianasilage

Identifiers

PMID32258012
PMCPMC7093594

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.