Evidence map›Paper›PMID 32257736›Full record

ArticleIEEE access : practical innovations, open solutions2020

Modality-specific deep learning model ensembles toward improving TB detection in chest radiographs.

Sivaramakrishnan Rajaraman, Sameer K Antani

Abstract read
In one paragraph

Article in IEEE access : practical innovations, open solutions, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 44 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
44citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

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3 · Its place in the literature

Who cites it

44 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Sivaramakrishnan RajaramanLister Hill National Center for Biomedical Communications, National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894 USA.
Sameer K AntaniLister Hill National Center for Biomedical Communications, National Library of Medicine, 8600 Rockville Pike, Bethesda, MD 20894 USA.

Funding

Machine learning and artificial intelligence algorithms for chest imaging diagnosticsZIALM010004 · NLM · NATIONAL LIBRARY OF MEDICINE · PI ANTANI, SAMEER · 2016 to 2020
$2.8M
Intramural NIH HHS Z99 LM999999
6 · The paper itself

Abstract

The proposed study evaluates the efficacy of knowledge transfer gained through an ensemble of modality-specific deep learning models toward improving the state-of-the-art in Tuberculosis (TB) detection. A custom convolutional neural network (CNN) and selected popular pretrained CNNs are trained to learn modality-specific features from large-scale publicly available chest x-ray (CXR) collections including (i) RSNA dataset (normal = 8851, abnormal = 17833), (ii) Pediatric pneumonia dataset (normal = 1583, abnormal = 4273), and (iii) Indiana dataset (normal = 1726, abnormal = 2378). The knowledge acquired through modality-specific learning is transferred and fine-tuned for TB detection on the publicly available Shenzhen CXR collection (normal = 326, abnormal =336). The predictions of the best performing models are combined using different ensemble methods to demonstrate improved performance over any individual constituent model in classifying TB-infected and normal CXRs. The models are evaluated through cross-validation (n = 5) at the patient-level with an aim to prevent overfitting, improve robustness and generalization. It is observed that a stacked ensemble of the top-3 retrained models demonstrates promising performance (accuracy: 0.941; 95% confidence interval (CI): [0.899, 0.985], area under the curve (AUC): 0.995; 95% CI: [0.945, 1.00]). One-way ANOVA analyses show there are no statistically significant differences in accuracy (

Indexed as

Classificationconfidence intervalconvolutional neural networkdeep learningensembleknowledge transfermodality-specific learningtuberculosis

Identifiers

PMID32257736
PMCPMC7120763

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.