Evidence map›Paper›PMID 32257462›Full record

ArticleCase reports in endocrinology2020

Langerhans Cell Histiocytosis of the Thyroid Leading to the Diagnosis of a Disseminated Form.

Ibtissem Ben Nacef, Sabrine Mekni, Chedi Mhedhebi, Ines Riahi, Imen Rojbi, Mchirgui Nadia, Karima Khiari

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in endocrinology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Ibtissem Ben NacefDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.ORCID https://orcid.org/0000-0003-1609-7022
Sabrine MekniDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.
Chedi MhedhebiDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.
Ines RiahiDepartment of Otorhinolaryngology-Head and Neck Surgery, Charles Nicolle Hospital, Tunis, Tunisia.
Imen RojbiDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.
Mchirgui NadiaDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.
Karima KhiariDepartment of Endocrinology, Charles Nicolle Hospital, Tunis, Tunisia.
Hôpital Charles-Nicolle · TN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Langerhans cell histiocytosis (LCH) is a rare sporadic proliferative disorder of Langerhans cells. LCH rarely involves the thyroid gland. We report herein a case of a disseminated chronic form of LCH with a diagnosis established by histological examination of the thyroid gland. It is about a 37-year-old female who underwent total thyroidectomy for a thyroid nodule of the right lobe. Histological study showed a granulomatous thyroiditis, and the immunohistochemistry study revealed a strong positivity of histiocytes for the CD1 antigen and for the S100 protein. The incidence of LCH involving the thyroid gland, either as an isolated lesion or as a part of multisystemic disease, is extremely rare.

Identifiers

PMID32257462
PMCPMC7103030
OpenAlexW3011619205

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.