ArticleComputational and mathematical methods in medicine2020
Homology Modeling and Virtual Screening Studies of Antigen MLAA-42 Protein: Identification of Novel Drug Candidates against Leukemia-An
Article in Computational and mathematical methods in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
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Who cites it
21 citing papers in PubMed.
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- Prospects of earthworm coelomic fluid as a potential therapeutic agent to treat cancer.Cancer metastasis reviews · 2024Review
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- Synthesis and molecular docking analysis of MBH adducts' derived amides as potentialBioinformation · 2024Article
- Identification of novel inhibitors against hantaviruses through 2D fingerprinting and molecular modeling approaches.Frontiers in immunology · 2023Article
- Design, synthetic approach,RSC advances · 2022Article
- Towards Covid-19 TMPRSS2 enzyme inhibitors and antimicrobial agents: Synthesis, antimicrobial potency, molecular docking, and drug-likeness prediction of thiadiazole-triazole hybrids.Journal of molecular structure · 2022Article
- Newly Synthesized Pyrazolinone Chalcones as Anticancer Agents via Inhibiting the PI3K/Akt/ERK1/2 Signaling Pathway.ACS omega · 2022Article
- Novel Thiadiazole-Based Molecules as Promising Inhibitors of Black Fungi and Pathogenic Bacteria: In Vitro Antimicrobial Evaluation and Molecular Docking Studies.Molecules (Basel, Switzerland) · 2022Article
- Synthesis, characterization,RSC advances · 2022Article
- Molecular docking and mouse modeling suggest CMKLR1 and INSR as targets for improving PCOS phenotypes by minocycline.EXCLI journal · 2022Article
- Synthesis, Identification, Computer-Aided Docking Studies, and ADMET Prediction of Novel Benzimidazo-1,2,3-triazole Based Molecules as Potential Antimicrobial Agents.Molecules (Basel, Switzerland) · 2021Article
- New Amino Acid Schiff Bases as Anticancer Agents via Potential Mitochondrial Complex I-Associated Hexokinase Inhibition and Targeting AMP-Protein Kinases/mTOR Signaling Pathway.Molecules (Basel, Switzerland) · 2021Article
- Synthesis, Molecular Docking Studies and In Silico ADMET Screening of New Heterocycles Linked Thiazole Conjugates as Potent Anti-Hepatic Cancer Agents.Molecules (Basel, Switzerland) · 2021Article
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- Eco-Friendly Synthesis, Biological Evaluation, andFrontiers in chemistry · 2021Article
- Synthesis, Molecular Docking Analysis andFrontiers in molecular biosciences · 2021Article
- Thiazole-Based Thiosemicarbazones: Synthesis, Cytotoxicity Evaluation and Molecular Docking Study.Drug design, development and therapy · 2021Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Monocytic leukemia-associated antigen-42 (MLAA-42) is associated with excessive cell division and progression of leukemia. Thus, human MLAA-42 is considered as a promising target for designing of new lead molecules for leukemia treatment. Herein, the 3D model of the target was generated by homology modeling technique. The model was then evaluated using various cheminformatics servers. Moreover, the virtual screening studies were performed to explore the possible binding patterns of ligand molecules to MLAA's active site pocket. Thirteen ligand molecules from the ChemBank
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