Evidence map›Paper›PMID 32256634›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2020

Research Progress on Anti-Inflammatory Effects and Mechanisms of Alkaloids from Chinese Medical Herbs.

Sicong Li, Xin Liu, Xiaoran Chen, Lei Bi

Open access · hybridAbstract readReview
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
6.5field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it, 62 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. The potential ofFuture science OA · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. [Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2024
    Article
  9. Review
  10. Article
  11. Article
  12. Phytochemical Profiling and Wound Healing Activity ofJournal of experimental pharmacology · 2024
    Article
  13. Review
  14. Review
  15. Metabolites · 2023
    Review
  16. Article
  17. Epiisopiloturine, an Alkaloid fromOxidative medicine and cellular longevity · 2023
    Article
  18. Article
  19. Antimalarial Properties ofEvidence-based complementary and alternative medicine : eCAM · 2023
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Sicong LiSchool of Pharmacy, Peking University Health Science Centre, Beijing, China.ORCID https://orcid.org/0000-0002-6414-6645
Xin LiuSchool of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing 100029, China.ORCID https://orcid.org/0000-0003-3593-3460
Xiaoran ChenSchool of Pharmacy, Peking University Health Science Centre, Beijing, China.
Lei BiSchool of Traditional Chinese Medicine, Beijing University of Traditional Chinese Medicine, Beijing 100029, China.
Beijing Hospital of Traditional Chinese Medicine · CNPeking University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

As the spectrum of diseases keeps changing and life pace keeps going faster, the probability and frequency of diseases caused by human inflammatory reactions also keep increasing. How to develop effective anti-inflammatory drugs has become the hotspot of researches. It has been found that alkaloids from Chinese medical herbs have anti-inflammatory, analgesic, antitumor, anticonvulsant, diuretic, and antiarrhythmic effects, among which the anti-inflammatory effect is very prominent and commonly used in the treatment of rheumatoid arthritis, ankylosing spondylitis, and other rheumatic immune diseases, but its mechanism of action has not been well explained. Based on this, this paper will classify alkaloids according to structural types and review the plant sources, applicable diseases, and anti-inflammatory mechanisms of 16 kinds of alkaloids commonly used in clinical treatment, such as berberine, tetrandrine, and stephanine, with the aim of providing a reference for drug researches and clinical applications.

Identifiers

PMID32256634
PMCPMC7104124
OpenAlexW3012432607

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.