ArticleJournal of oncology2020
Identification and Resolution of Drug-Related Problems among Childhood Cancer Patients in Ethiopia.
Article in Journal of oncology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 3 of them syntheses that pooled it.
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Who cites it
13 citing papers in PubMed, 3 syntheses or guidelines pooled it, 30 citations in OpenAlex.
- Medication-related problems and their associated factors among paediatric patients in Ethiopia: a systematic review and meta-analysis.BMJ paediatrics open · 2026Pooled it
- Prevalence of medication-related problems and its predictors among cancer patients in Ethiopia: A systematic review and meta-analysis.PloS one · 2026Pooled it
- Systematic review of the prevalence and nature of drug-related problems in paediatric patients.Journal of clinical pharmacy and therapeutics · 2022Pooled it
- Impact of clinical pharmacist-led medication management and education on tacrolimus therapeutic control.Frontiers in medicine · 2026Article
- Drug-related problems and their predictors in pediatric community-acquired infections: the role of pharmacist-led interventions in Pakistan.Journal of pharmacy & pharmaceutical sciences : a publication of the Canadian Society for Pharmaceutical Sciences, Societe canadienne des sciences pharmaceutiques · 2026Article
- Chemotherapy-Induced Toxicities in Pediatric Cancer Patients: A Cross-Sectional Survey Using a Child- and Caregiver-Reported Outcome Tool in Tanzania.Drug, healthcare and patient safety · 2026Article
- Systematic review and meta-analysis of chemotherapy-induced adverse drug reactions among children with cancer in Africa.Infectious agents and cancer · 2025Review
- Assessment of drug-related problems among breast cancer patients in a cancer specialty center in Nepal.PloS one · 2025Article
- Investigating pediatric nurses' perceptions of factors contributing to MAEs at Yendi hospital, Ghana.BMC pediatrics · 2024Article
- Adverse drug reactions and drug-related problems with supportive care medications among the oncological population.Discover oncology · 2024Article
- Determinants of medication non-adherence among patients with chronic diseases at community pharmacy settings in South Gondar Zone, Northwest Ethiopia: a multicenter cross-sectional study.Frontiers in public health · 2024Article
- Effect of Pharmacist-Led Interventions on Physicians' Prescribing for Pediatric Outpatients.Healthcare (Basel, Switzerland) · 2022Article
- Management Practice and Drug Related Problems and Its Contributing Factors Among Cervical Cancer Patients at Oncologic Center in Ethiopia: A Hospital-Based Retrospective Study.Therapeutics and clinical risk management · 2022Article
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Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundEven though medications play a major role in the cure, palliation, and inhibition of disease, they also expose patients to drug-related problems. Drug-related problems are frequent and may result in reduced quality of life, morbidity, and mortality.
objectivesThe study was aimed to identify, characterize, and resolve drug-related problems in the Pediatric Hematology/Oncology ward of Tikur Anbessa Specialized Hospital, Addis Ababa, Ethiopia.
methodsA prospective observational study was conducted from 25 June to 25 October 2018 to assess DRPs on patients admitted at the pediatric hematology/oncology ward of Tikur Anbessa Specialized Hospital, which is the highest level governmental tertiary care hospital in Ethiopia. Data were obtained from patients' medical charts, physicians, patients/caregivers, pharmacists, and nurses. All the collected data were entered and analyzed using the Statistical Package for the Social Sciences version 25e. Descriptive statistics were used to represent the data.
resultsAmong the total 156 participants, DRPs were identified in 68.6% of the study subjects. Dosing problems which include dosage too low and high were the top ranking (39.3%) of all DRPs followed by needs additional therapy (27.2%) and nonadherence (14.0%). Systemic anti-infectives were the most common class of drugs involved in DRPs. Trimethoprim-sulfamethoxazole, methotrexate, vincristine, ondansetron, and metoclopramide were frequently involved in DRPs. The addition of drugs and change in drug dose were the two most proposed intervention types. Among the proposed interventions, 223 (92.15%) were fully accepted, 9 (3.72%) partially accepted, and 10 (4.13%) not accepted.
conclusionDRPs are common among Pediatric Hematology/Oncology ward patients. The hospital should develop a pediatric dosing chart for the commonly prescribed medications to prevent drug-related morbidity and mortality. The integration of clinical pharmacists can mitigate risks associated with DRPs.
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