Evidence map›Paper›PMID 32256497›Full record

ArticleFrontiers in immunology2020

Influenza-Induced Interferon Lambda Response Is Associated With Longer Time to Delivery Among Pregnant Kenyan Women.

Christof Seiler, Nicholas L Bayless, Rosemary Vergara, Jillian Pintye, John Kinuthia, Lusi Osborn, Daniel Matemo, Barbra A Richardson, Grace John-Stewart, Susan Holmes and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.1field-weighted citation impact, top 60% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 5 institutions in 3 countries.

Christof SeilerDepartment of Statistics, Stanford University, Stanford, CA, United States.
Nicholas L BaylessImmunology Program, Stanford University School of Medicine, Stanford, CA, United States.
Rosemary VergaraDepartment of Medicine, Stanford University School of Medicine, Stanford, CA, United States.
Jillian PintyeDepartment of Global Health, University of Washington School of Medicine, Seattle, WA, United States.
John KinuthiaKenyatta National Hospital, Nairobi, Kenya.
Lusi OsbornKenyatta National Hospital, Nairobi, Kenya.
Daniel MatemoKenyatta National Hospital, Nairobi, Kenya.
Barbra A RichardsonDepartment of Global Health, University of Washington School of Medicine, Seattle, WA, United States.
Grace John-StewartDepartment of Global Health, University of Washington School of Medicine, Seattle, WA, United States.
Susan HolmesDepartment of Statistics, Stanford University, Stanford, CA, United States.
Catherine A BlishImmunology Program, Stanford University School of Medicine, Stanford, CA, United States.
Kenyatta National Hospital · KEStanford University · USUniversity of Washington · USChan Zuckerberg Initiative (United States) · USMaastricht University · NL

Funding

Vaginal Health and the Risk of HIV-1 Acquistion in Kenyan WomenP01HD064915 · NICHD · FRED HUTCHINSON CANCER RESEARCH CENTER · PI MCCLELLAND, RAYMOND SCOTT · 2009 to 2013
$8.9M
Targeting natural killer cells to HIV in intravenous drug usersDP1DA046089 · NIDA · STANFORD UNIVERSITY · PI BLISH, CATHERINE A · 2018 to 2022
$3.9M
Infant immune mechanisms of HIV reservoir size and decayR01HD094718 · NICHD · UNIVERSITY OF WASHINGTON · PI JOHN-STEWART, GRACE C., LEHMAN, DARA ANN · 2017 to 2021
$3.6M
Impact of HIV exposure, feeding status, and microbiome on immune ontogeny and vaccine responses in infantsU01AI131302 · NIAID · STANFORD UNIVERSITY · PI BLISH, CATHERINE A, GRAY, CLIVE MAURICE · 2017 to 2021
$2.1M
Mechanisms by which trophoblasts recruit T cells to the placental villi during maternal HIV and CMV co-infectionR21HD103498 · NICHD · MAYO CLINIC ROCHESTER · PI CHAKRABORTY, RANA, GRAY, CLIVE MAURICE · 2020 to 2021
$390k
Functional and transcriptional signatures of preterm birthF31HD089675 · NICHD · STANFORD UNIVERSITY · PI BAYLESS, NICHOLAS LOGAN · 2016 to 2016
$25k
NIAID NIH HHS U01 AI131302NICHD NIH HHS F31 HD089675NICHD NIH HHS P01 HD064915NICHD NIH HHS R01 HD094718NICHD NIH HHS R21 HD103498NIDA NIH HHS DP1 DA046089
6 · The paper itself

Abstract

Specific causes of preterm birth remain unclear. Several recent studies have suggested that immune changes during pregnancy are associated with the timing of delivery, yet few studies have been performed in low-income country settings where the rates of preterm birth are the highest. We conducted a retrospective nested case-control evaluation within a longitudinal study among HIV-uninfected pregnant Kenyan women. To characterize immune function in these women, we evaluated unstimulated and stimulated peripheral blood mononuclear cells

Indexed as

Case-Control StudiesCells, CulturedDelivery, ObstetricFemaleGene Expression ProfilingHumansInfluenza, HumanInterferon LambdaInterferonsInterleukinsKenyaOrthomyxoviridaePregnancyPregnancy OutcomePremature BirthRetrospective StudiesInterferon Lambdainterferon-lambda, humanInterferonsInterleukinsimmuneinfluenza virusinterferonpregnancypretermtime to delivery

Identifiers

PMID32256497
PMCPMC7089959
OpenAlexW3011163207

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.