ArticleFrontiers in psychiatry2020
Decision-Making Under Ambiguity or Risk in Individuals With Alzheimer's Disease and Mild Cognitive Impairment.
Article in Frontiers in psychiatry, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 39 citations in OpenAlex.
- Practical judgment in aging: examining behavioral vulnerabilities and neurobiological correlates.Frontiers in psychology · 2026Article
- Attenuated neural activity in processing decision-making feedback in uncertain conditions in patients with mild cognitive impairment.European archives of psychiatry and clinical neuroscience · 2025Article
- Disruption of hippocampal-prefrontal neural dynamics and risky decision-making in a mouse model of Alzheimer's disease.Cell reports · 2025Article
- Caudal and Thalamic Segregation in White Matter Brain Network Communities in Alzheimer's Disease Population.... IEEE-EMBS International Conference on Biomedical and Health Informatics. IEEE-EMBS International Conference on Biomedical and Health Informatics · 2024Article
- Late-life psychiatric factors and life satisfaction are associated with cognitive errors: evidence from an experimental module of a large-scale survey in India.Scientific reports · 2024Article
- Cognitive, Emotional, and Daily Functioning Domains Involved in Decision-Making among Patients with Mild Cognitive Impairment: A Systematic Review.Brain sciences · 2024Review
- Dorsal and ventral fronto-amygdala networks underlie risky decision-making in age-related cognitive decline.GeroScience · 2024Article
- Risk-Taking Behavior Differs Between Older Adults with and without Mild Cognitive Impairment.Journal of Alzheimer's disease : JAD · 2024Article
- Shared Decision Making for Elective Surgical Procedures in Older Adults with and without Cognitive Insufficiencies.Medical decision making : an international journal of the Society for Medical Decision Making · 2023Article
- Shared decision-making in persons living with dementia: A scoping review.Dementia (London, England) · 2023Article
- Enhanced putamen functional connectivity underlies altered risky decision-making in age-related cognitive decline.Scientific reports · 2023Article
- Aging-related changes in reward-based decision-making depend on punishment frequency: An fMRI study.Frontiers in aging neuroscience · 2023Article
- The Effects of Tinnitus in Probabilistic Learning Tasks: Protocol for an Ecological Momentary Assessment Study.JMIR research protocols · 2022Article
- Decision making under ambiguity and risk in adolescent-onset schizophrenia.BMC psychiatry · 2021Article
- [Position paper of the Austrian Alzheimer Association (Österreichische Alzheimer Gesellschaft, ÖAG) : Effects of the COVID-19 pandemic in Austria on people with dementia and their care environment-problem areas, recommendations, and strategies].Neuropsychiatrie : Klinik, Diagnostik, Therapie und Rehabilitation : Organ der Gesellschaft Osterreichischer Nervenarzte und Psychiater · 2021Article
- Decision-Making Support for People With Alzheimer's Disease: A Narrative Review.Frontiers in psychology · 2021Review
- Evaluating the Effects of Rivastigmine on Decision-Making in Patients with Mild Cognitive Impairment by Cambridge Neuropsychological Test Automated Battery (CANTAB); A Randomized, Double-Blind, Placebo-Controlled Trial.Iranian journal of pharmaceutical research : IJPRArticle
Corrections and comments
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Authors and funding
8 authors at 4 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundMaking advantageous decisions is essential in everyday life. Our objective was to assess how patients with mild cognitive impairment (MCI) and Alzheimer's disease (AD) make decisions under conditions of ambiguity or risk. In addition, the study also aimed to examine the relationship between decision-making competence and memory and executive function.
methodsPatients with MCI (n = 36) and AD (n = 29) and healthy elderly controls (HC, n = 34) were recruited from the memory clinic. All subjects were administered a comprehensive neuropsychological battery test. We used the Iowa Gambling Task (IGT) to measure decision-making under ambiguity and the Game of Dice Task (GDT) to measure decision-making under risk. Pearson's correlation was used to examine the relationship between the performance of IGT and GDT with delayed recall and the Stroop test.
resultsIn the GDT, MCI and AD patients presented similar performance but showed different patterns when compared with the HC group. The proportion of those making advantageous choices was lower in the AD group than in the HC group (
conclusionOur findings suggest that decision-making ability under ambiguity is compromised in MCI and AD, and the decision-making under risk is only impaired in AD. Reduced decision-making performance under risk is closely correlated with lower executive functions and memory.
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