Evidence map›Paper›PMID 32256349›Full record

ArticleFrontiers in pharmacology2020

Astragalus Polysaccharides/Chitosan Microspheres for Nasal Delivery: Preparation, Optimization, Characterization, and Pharmacodynamics.

Saisai Wang, Yuqing Sun, Jingjing Zhang, Xiaoming Cui, Zhilu Xu, Dejun Ding, Limin Zhao, Wentong Li, Weifen Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.1field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 24 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Current issues in molecular biology · 2024
    Review
  5. Review
  6. Design and Application in Delivery System of Intranasal Antidepressants.Frontiers in bioengineering and biotechnology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Saisai WangSchool of Pharmacy, Weifang Medical University, Weifang, China.
Yuqing SunDepartment of Otolaryngology, Head and Neck Surgery, Central Hospital of Zibo, Zibo, China.
Jingjing ZhangCollege of Basic Medical, Qingdao Binhai University, Qingdao, China.
Xiaoming CuiSchool of Pharmacy, Weifang Medical University, Weifang, China.
Zhilu XuSchool of Pharmacy, Weifang Medical University, Weifang, China.
Dejun DingSchool of Pharmacy, Weifang Medical University, Weifang, China.
Limin ZhaoDepartment of Otolaryngology, Head and Neck Surgery, Affiliated Hospital of Weifang Medical University, Weifang, China.
Wentong LiShandong Engineering Research Center for Smart Materials and Regenerative Medicine, Weifang Medical University, Weifang, China.
Weifen ZhangSchool of Pharmacy, Weifang Medical University, Weifang, China.
Weifang Medical University · CNCentral Hospital of Zibo · CNQingdao Binhai University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chitosan (CTS) constitutes a promising area in treatment of nose-related diseases as a nasal drug delivery carrier. Astragalus polysaccharide (APS) significantly attenuates eosinophils and neutrophil-dominant airway inflammation, and it has a potential pharmaceutical application in the treatment of severe asthma. The purpose of this work was to prepare APS/CTS microspheres intended for nasal drug delivery by the spray-drying method. The characteristics of APS/CTS microspheres were evaluated by a scanning electron microscope, Fourier transform infrared spectroscopy, differential scanning calorimetry, and

Indexed as

Astragalus polysaccharideChitosanmicrospheresnasal drug deliveryspray drying

Identifiers

PMID32256349
PMCPMC7093564
OpenAlexW3011678012

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.