ReviewOpen access emergency medicine : OAEM2020
Management of Alcohol Withdrawal in the Emergency Department: Current Perspectives.
Review in Open access emergency medicine : OAEM, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Phenobarbital treatment of alcohol withdrawal in the emergency department: A systematic review and meta-analysis.Academic emergency medicine : official journal of the Society for Academic Emergency Medicine · 2024Pooled it
- Behavioral and Psychosocial Predictors of Treatment Response in Emergency Psychiatric Admissions for Substance Use Disorders in a Socioeconomically Vulnerable Region of Southeastern Romania: A Five-Year Retrospective Study.Behavioral sciences (Basel, Switzerland) · 2026Article
- Article
- Health impact of alcohol use in the USA: a protocol of a systematic review and modelling study.BMJ open · 2025Article
- Alcohol-induced psychosis and delirium tremens: a comparison with alcohol dependence on demographic characteristics, mortality, and morbidity.BMC psychiatry · 2025Article
- Emergency care utilization in persons with substance related diagnoses.Addictive behaviors reports · 2024Article
- Views and experiences of involuntary civil commitment of people who use drugs in Massachusetts (Section 35).Drug and alcohol dependence · 2024Article
- Alterations in Neurotrophins in Alcohol-Addicted Patients during Alcohol Withdrawal.Brain sciences · 2024Review
- Article
- The possible clinical utility of the alcohol biomarker phosphatidylethanol for managing suspected alcohol withdrawal in hospitalized patients: A case report.The American journal on addictions · 2024Article
- Delirium Tremens: A Review of Clinical Studies.Cureus · 2024Review
- Prevalence and Predictors of Non-Benzodiazepine Use in Patients with Alcohol Withdrawal Syndrome in United States Emergency Departments - a cross-sectional study.Innovations in pharmacy · 2024Article
- Flow through the Emergency Department for Patients Presenting with Substance Use Disorder in Alberta, Canada.The western journal of emergency medicine · 2023Article
- Alcohol Withdrawal with Delirium Tremens.Journal of education & teaching in emergency medicine · 2023Article
- Delirium in a surgical context from a nursing perspective: A hybrid concept analysis.International journal of nursing studies advances · 2022Article
- Diagnostic Performance of AST Scale in Mexican Male Population for Alcohol Withdrawal Syndrome.International journal of environmental research and public health · 2022Article
- Provider perspectives on emergency department initiation of medication assisted treatment for alcohol use disorder.BMC health services research · 2022Article
- Prevention of alcohol withdrawal seizure recurrence and treatment of other alcohol withdrawal symptoms in the emergency department: a rapid review.BMC emergency medicine · 2021Review
- Acceptability Among Frontline Staff Toward Distributing an Anonymous Alcohol Survey in Emergency Departments: A Mixed Methods Study.Journal of addictions nursingArticle
- Clinical characteristics and health outcomes in patients with alcohol withdrawal syndrome: an observational study from Oman.Annals of Saudi medicineObservational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Alcohol withdrawal syndrome (AWS) is a common, heterogenous, and life-threatening complication of alcohol use disorder (AUD). AUD is a leading cause of worldwide mortality, and many patients with AUD will develop AWS during their ED course. This review summarizes the epidemiology, pathology, and management of AWS and AUD in the emergency setting. The time course of AWS and its impact on ED treatment is emphasized. Once AWS is diagnosed, symptom-triggered benzodiazepine administration remains the most commonly provided treatment but may not be appropriate for patients with significant medical or psychiatric comorbidity or pending discharge. In these cases, ED clinicians may consider short courses of barbiturates or alternative regimens based on novel anticonvulsants. Specific treatment protocols are enumerated for clinical practice. Finally, emergency providers must not only manage acute patients' AWS but also lay the foundation for successful treatment of AUD. An approach to the disposition of the patient with AUD is presented. The authors examine shortcomings in the extant literature and suggest opportunities for further study.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.