ArticlePatient preference and adherence2020
User Acceptability and Technical Robustness Evaluation of a Novel Smart Pill Bottle Prototype Designed to Support Medication Adherence.
Article in Patient preference and adherence, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06522698 (Optimizing Research Data Acquisition With Smart Pill Bottles), which is not on this map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Optimizing Research Data Acquisition With Smart Pill Bottles: A Feasibility and Implementation Study
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Effectiveness of Mobile Medical Apps in Ensuring Medication Safety Among Patients With Chronic Diseases: Systematic Review and Meta-analysis.JMIR mHealth and uHealth · 2022Pooled it
- Trial
- Smart Blister System with and without Mobile App Support: A Randomized Controlled Usability Trial.Patient preference and adherence · 2026Article
- Sea Horse Optimization-Deep Neural Network: A Medication Adherence Monitoring System Based on Hand Gesture Recognition.Sensors (Basel, Switzerland) · 2024Article
- A Systematic Review on Pill and Medication Dispensers from a Human-Centered Perspective.Journal of healthcare informatics research · 2024Article
- Beliefs of patients who visited community pharmacies about medicines and supplements, the need for drug therapy and medication adherence - a cross-sectional study.Journal of pharmaceutical policy and practice · 2024Article
- Article
- Survey of Transfer Learning Approaches in the Machine Learning of Digital Health Sensing Data.Journal of personalized medicine · 2023Review
- Acceptance and Usability of an Innovative mDentistry eHygiene Model Amid the COVID-19 Pandemic Within the US National Dental Practice-Based Research Network: Mixed Methods Study.JMIR human factors · 2023Article
- Half a Century of Fragmented Research on Deviations from Advised Therapies: Is This a Good Time to Call for Multidisciplinary Medication Adherence Research Centres of Excellence?Pharmaceutics · 2023Article
- Review of glaucoma medication adherence monitoring in the digital health era.The British journal of ophthalmology · 2023Review
- Usability and perceived usefulness of patient-centered medication reconciliation using a personalized health record: a multicenter cross-sectional study.BMC health services research · 2022Article
- Technologies for Medication Adherence Monitoring and Technology Assessment Criteria: Narrative Review.JMIR mHealth and uHealth · 2022Review
- Reimbursed Medication Adherence Enhancing Interventions in European Countries: Results of the EUREcA Study.Frontiers in pharmacology · 2022Article
- Electronic Smart Blister Packages to Monitor and Support Medication Adherence: A Usability Study.Patient preference and adherence · 2022Article
- Assessment of an Innovative Mobile Dentistry eHygiene Model Amid the COVID-19 Pandemic in the National Dental Practice-Based Research Network: Protocol for Design, Implementation, and Usability Testing.JMIR research protocols · 2021Article
- User Perception of Automated Dose Dispensed Medicine in Home Care: A Scoping Review.Healthcare (Basel, Switzerland) · 2021Article
- How Patient Work Changes Over Time for People With Multimorbid Type 2 Diabetes: Qualitative Study.Journal of medical Internet research · 2021Article
- European Network to Advance Best Practices and Technology on Medication Adherence: Mission Statement.Frontiers in pharmacology · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeSmart medication adherence monitoring devices can provide objective and granular drug utilization data and help patients engaging with their treatment. In this proof-of-concept study, the acceptability and technical robustness of a novel smart pill bottle prototype (SPBP) were assessed in order to allow further optimization.
methodsThe SPBP is an app-controlled automatic dispense system, capturing real-time data on a web-based platform, which sends text reminders and measures storage conditions. A heterogeneous group of ten volunteers was asked to dispense placebo capsules with the SPBP and to follow a predefined dosing schedule for a trial period of 2 weeks. Afterwards, a questionnaire was filled out during a short interview. Primary outcome was dispense adherence as measured by the bottle. Other study outcomes included system acceptability (System Usability Scale [SUS]), self-reported adherence (MARS) and technical robustness of the bottle's mechanics (electronic pill dispenser) and sensors (bottle temperature).
resultsThe overall dispense adherence rate as measured by the SPBP was 88%. All participants completed the study and four participants had an adherence rate of 100% during the study. The dispense adherence rates corresponded well with participants' self-reported adherence with an average MARS total score of 23.6 (out of 25). Participants judged the system easy to use, with a mean SUS score of 79.3 (range: 57.5-97.5). The overall mean temperature difference between the bottle sensor and calibrated external sensor was -0.82°C (range: -1.37°C to -0.21°C).
conclusionThe SPBP was well accepted and this study provides data for further optimization and follow-up studies. Smart adherence technologies such as these may change the way healthcare professionals, trialists and patients manage medication adherence.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.