Evidence map›Paper›PMID 32255918›Full record

ArticleLaser therapy2019

Intravenous Laser Wavelength Irradiation Effect on Interleukins: IL-1α, IL-1β, IL6 in Diabetic Rats.

A Amjadi, H Mirmiranpor, S Khandani, S O Sobhani, Y Shafaee

Open access · diamondAbstract read
In one paragraph

Article in Laser therapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

A Amjadi(Corresponding Author) Laser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran, E-mail: amjadi@sharif.edu, Tel: +98-2166164521 Fax:+98-2166022711.
H MirmiranporEndocrinology and Metabolism Research Center (EMRC), Valiasr Hospital, School of Medicine, Tehran University of Medical Science, Tehran, Iran, E-mail: h_mirmiranpoor@yahoo.com, Tel: +98-9123388654.
S KhandaniLaser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran, E-mail: salile.kh100@gmail.com, Tel.: +98-9155828735.
S O SobhaniLaser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran, E-mail: omid.sobhani@gmail.com, Tel.: +32-494903687.
Y ShafaeeLaser and Medical Physics Lab, Department of Physics, Sharif University of Technology, Tehran, Iran, E-mail: Yasaman_shafaee@yahoo.com, Tel.: +98-9101030472.
Sharif University of Technology · IRUniversity of Tehran · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimsThe main purpose of this investigation in Low-Level Laser Therapy (LLLT) on diabetic rats is laser wavelength effect on interleukins: IL-1α, IL-1β, IL6. MATERIALS SUBJECTS AND

methodsAt first, diabetes was induced in Wistar rats by streptozotocin (STZ) injection. Then, by intravenous laser therapy, the rats were irradiated by four continuous wave lasers: IR (λ = 808 nm), Red (λ = 638 nm), Green (λ = 532 nm) and Blue (λ= 450 nm) to compare the related laser wavelength effect on different interleukins. The inflammatory parameters were measured 2,6 and 24 hours after laser therapy from blood samples and plotted for different laser wavelengths.

resultsThe results show a decrease in all the above parameters by different laser irradiation in comparison to non-radiated diabetic control ones. More importantly with constant laser energy as the laser wavelength decreases, it affects more efficiently on lowering the above parameters.

conclusionswe can conclude from our data on diabetic rats that in intravenous LLLT, with constant laser energy, shorter wavelengths like Blue (λ= 450 nm) is more effective than longer wavelengths such as Red (λ = 638 nm) and IR (λ = 808 nm) lasers to lower the level of interleukins toward non-diabetic ones.

Indexed as

DiabetesiIL-1αIL1-βIL6InflammationLow Level Laser Therapy

Identifiers

PMID32255918
PMCPMC7087337
OpenAlexW3003679200

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.