Evidence map›Paper›PMID 32255425›Full record

ArticleeLife2020

Cell and molecular transitions during efficient dedifferentiation.

John Me Nichols, Vlatka Antolović, Jacob D Reich, Sophie Brameyer, Peggy Paschke, Jonathan R Chubb

Open access · goldAbstract read
In one paragraph

Article in eLife, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 35 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Single Cell Transcriptome Analysis During Development in Dictyostelium.Methods in molecular biology (Clifton, N.J.) · 2024
    Article
  8. Article
  9. The Growing Liberality Observed in Primary Animal and Plant Cultures is Common to the Social Amoeba.Journal of bioinformatics and systems biology : Open access · 2023
    Article
  10. Cell plasticity in regeneration in the stomach and beyond.Current opinion in genetics & development · 2022
    Review
  11. Article
  12. Review
  13. Transcriptional milestones inGenome research · 2021
    Article
  14. Article
  15. Article
  16. Article
  17. Decanoic acid inhibits mTORC1 activity independent of glucose and insulin signaling.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 2 countries.

John Me NicholsMRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.ORCID 0000-0003-2061-1485
Vlatka AntolovićMRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.ORCID 0000-0002-1943-1850
Jacob D ReichMRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.
Sophie BrameyerLudwig-Maximilians-University Munich, Martinsried, Germany.ORCID 0000-0002-6779-2343
Peggy PaschkeCRUK Beatson Institute, Garscube Estate, Switchback Road, Bearsden, Glasgow, United Kingdom.
Jonathan R ChubbMRC Laboratory for Molecular Cell Biology and Department of Cell and Developmental Biology, University College London, London, United Kingdom.ORCID 0000-0001-6898-9765
MRC Laboratory for Molecular Cell Biology · GBCancer Research UK Scotland Institute · GBLudwig-Maximilians-Universität München · DE

Funding

Medical Research Council MC_U12266B
6 · The paper itself

Abstract

Dedifferentiation is a critical response to tissue damage, yet is not well understood, even at a basic phenomenological level. Developing

Indexed as

Gene ExpressionMutationCell DedifferentiationDictyosteliumGene Expression ProfilingSingle-Cell AnalysisTranscription FactorsTranscription Factorsbet-hedgingcell plasticitydedifferentiationdevelopmental biologydictyosteliumDictyosteliuminduced pluripotent stem cellsregenerative medicinereprogrammingstem cells

Identifiers

PMID32255425
PMCPMC7190356
OpenAlexW3014679506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.