ArticleJournal of neurotrauma2020
Brain Tissue Oxygen and Cerebrovascular Reactivity in Traumatic Brain Injury: A Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury Exploratory Analysis of Insult Burden.
Open access · greenAbstract readMulticenter Study
In one paragraph
Article in Journal of neurotrauma, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed
3.8field-weighted citation impact, top 5% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
26 citing papers in PubMed, 62 citations in OpenAlex.
- Prognostic Value of Cerebrovascular Reactivity (PRx) Versus Intracranial Pressure (ICP) Monitoring in Traumatic Brain Injury: Systematic Review.Journal of clinical medicine · 2026Review
- Lead times in the early management of traumatic brain injury: relation to geographic conditions and clinical outcomes in a nationwide Swedish registry study.Acta neurochirurgica · 2026Observational
- Early Autonomic Dysfunction Following Severe TBI and Impact on Cerebral Hemodynamics: A Narrative Review.Journal of clinical medicine · 2026Review
- Optimal cerebrovascular reactivity thresholds for the determination of individualized intracranial pressure thresholds in traumatic brain injury: a CAHR-TBI cohort study.Critical care (London, England) · 2025Article
- Continuous personalized cerebrovascular reactivity-based physiologic metrics in neurocritical care: a narrative review of the current landscape, limitations, and future directions.Frontiers in physiology · 2025Review
- Cerebral physiologic insult burden in acute traumatic neural injury: a Canadian High Resolution-TBI (CAHR-TBI) descriptive analysis.Critical care (London, England) · 2024Article
- Associations Between Intracranial Pressure Extremes and Continuous Metrics of Cerebrovascular Pressure Reactivity in Acute Traumatic Neural Injury: A Scoping Review.Neurotrauma reports · 2024Article
- Brain tissue oxygen monitoring in traumatic brain injury: part I-To what extent does PbtOCritical care (London, England) · 2023Article
- The impact of sedative and vasopressor agents on cerebrovascular reactivity in severe traumatic brain injury.Intensive care medicine experimental · 2023Article
- Non-Invasive Mapping of Cerebral Autoregulation Using Near-Infrared Spectroscopy: A Study Protocol.Methods and protocols · 2023Article
- The lower limit of reactivity as a potential individualised cerebral perfusion pressure target in traumatic brain injury: a CENTER-TBI high-resolution sub-study analysis.Critical care (London, England) · 2023Article
- Multimodal and autoregulation monitoring in the neurointensive care unit.Frontiers in neurology · 2023Review
- Intracranial Pressure Monitoring and Treatment Thresholds in Acute Neural Injury: A Narrative Review of the Historical Achievements, Current State, and Future Perspectives.Neurotrauma reports · 2023Article
- Cerebrovascular Reactivity Is Not Associated With Therapeutic Intensity in Adult Traumatic Brain Injury: A Validation Study.Neurotrauma reports · 2023Article
- Prolonged Automated Robotic TCD Monitoring in Acute Severe TBI: Study Design and Rationale.Neurocritical care · 2022Observational
- Hierarchical Cluster Analysis Identifies Distinct Physiological States After Acute Brain Injury.Neurocritical care · 2022Observational
- Initial neurocritical care of severe traumatic brain injury: New paradigms and old challenges.Surgical neurology international · 2022Review
- Intracranial Pressure-Derived Cerebrovascular Reactivity Indices, Chronological Age, and Biological Sex in Traumatic Brain Injury: A Scoping Review.Neurotrauma reports · 2022Article
- Evaluation of the relationship between slow-waves of intracranial pressure, mean arterial pressure and brain tissue oxygen in TBI: a CENTER-TBI exploratory analysis.Journal of clinical monitoring and computing · 2021Article
- Advanced Bio-signal Analytics for Continuous Bedside Monitoring of Aneurysmal Subarachnoid Hemorrhage: The Future.Neurocritical care · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors at 5 institutions in 4 countries.
Frederick A ZeilerDivision of Anaesthesia, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Erta BeqiriBrain Physics Laboratory, Division of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Manuel CabeleiraBrain Physics Laboratory, Division of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Peter J HutchinsonDepartment of Clinical Neurosciences, Division of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Nino StocchettiNeuro ICU Fondazione IRCCS Cà Granda Ospedale Maggiore Policlinico, Milan, Italy.
David K MenonDivision of Anaesthesia, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Marek CzosnykaBrain Physics Laboratory, Division of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Peter SmielewskiBrain Physics Laboratory, Division of Neurosurgery, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Ari ErcoleDivision of Anaesthesia, Addenbrooke's Hospital, University of Cambridge, Cambridge, United Kingdom.
Collaborative European NeuroTrauma Effectiveness Research in Traumatic Brain Injury (CENTER-TBI) High-Resolution ICU (HR ICU) Sub-Study Participants and Investigators
Addenbrooke's Hospital · GBUniversity of Cambridge · GBManitoba Health · CAUniversity of Milan · ITWarsaw University of Technology · PL
Funding
CIHR
Abstract
Pressure reactivity index (PRx) and brain tissue oxygen (PbtO
Indexed as
Cost of IllnessIntersectoral CollaborationAdultAgedBiomedical ResearchBrainBrain Injuries, TraumaticCerebrovascular CirculationCohort StudiesEuropeFemaleGlasgow Outcome ScaleHumansMaleMiddle AgedOxygen Consumptionautoregulationbrain tissue oxygenICPphysiological burden
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.