Evidence map›Paper›PMID 32253815›Full record

ReviewCancer medicine2020

Chemokines and chemokine receptors: A new strategy for breast cancer therapy.

Hui Liu, Zhenjiang Yang, Wenping Lu, Zhen Chen, Lianyu Chen, Shuyan Han, Xiaoyu Wu, Tiange Cai, Yu Cai

Open access · goldAbstract readReview
In one paragraph

Review in Cancer medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 67 papers.

0numbers the graph read from it
0cells of the map it votes in
67citing papers in PubMed
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

67 citing papers in PubMed, 120 citations in OpenAlex.

  1. Article
  2. Review
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  8. GPCR drug discovery: new agents, targets and indications.Nature reviews. Drug discovery · 2025
    Review
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  20. Identification and validation of the association of Janus kinase 2 mutations with the response to immune checkpoint inhibitor therapy.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2024
    Article

7 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 2 countries.

Hui LiuCollege of Pharmacy, Jinan University, Guangzhou, China.
Zhenjiang YangShenzhen Traditional Chinese Medicine Hospital, Shenzhen, China.
Wenping LuGuangan' Men Hospital China Academy of Chinese Medical Sciences, Beijing, China.
Zhen ChenDepartment of Integrative Oncology, Cancer Center, Fudan University, Shanghai, China.
Lianyu ChenDepartment of Integrative Oncology, Cancer Center, Fudan University, Shanghai, China.
Shuyan HanDepartment of Integration of Chinese and Western Medicine, Key Laboratory of Carcinogenesis and Translational Research (Ministry of Education), Peking University Cancer Hospital & Institute, Beijing, China.
Xiaoyu WuLeslie Dan Faculty of Pharmacy, University of Toronto, Toronto, Canada.
Tiange CaiCollege of Life Sciences, Liaoning University, Shenyang, China.
Yu CaiCollege of Pharmacy, Jinan University, Guangzhou, China.ORCID 0000-0002-8532-7816
Jinan University · CNShanghai Medical College of Fudan University · CNChinese Academy of Medical Sciences & Peking Union Medical College · CNLiaoning University · CNPeking University · CNShenzhen Pingle Orthopedic Hospital · CNUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chemokines and chemokine receptors not only participate in the development of tissue differentiation, hematopoiesis, inflammation, and immune regulation but also play an important role in the process of tumor development. The role of chemokines and chemokine receptors in tumors has been emphasized in recent years. More and more studies have shown that chemokines and chemokine receptors are closely related to the occurrence, angiogenesis, metastasis, drug resistance, and immunity of breast cancer. Here, we review recent progression on the roles of chemokines and chemokine receptors in breast cancer, and discuss the possible mechanism in breast cancer that might facilitate the development of new therapies by targeting chemokines as well as chemokine receptors. Chemokines and chemokine receptors play an important role in the occurrence and development of breast cancer. In-depth study of chemokines and chemokine receptors can provide intervention targets for breast cancer biotherapy. The regulation of chemokines and chemokine receptors may become a new strategy for breast cancer therapy.

Indexed as

Molecular Targeted TherapyAnimalsAntineoplastic AgentsBreast NeoplasmsChemokinesFemaleHumansInflammationNeovascularization, PathologicReceptors, ChemokineAntineoplastic AgentsChemokinesReceptors, Chemokinebreast cancerchemokine receptorschemokinestherapeutic target

Identifiers

PMID32253815
PMCPMC7286460
OpenAlexW3014352023

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.