Evidence map›Paper›PMID 32253799›Full record

ReviewDermatologic therapy2020

Generalized pustular figurate erythema: A newly delineated severe cutaneous drug reaction linked with hydroxychloroquine.

Robert A Schwartz, Camila K Janniger

Abstract readReview
In one paragraph

Review in Dermatologic therapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed, 4 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 4 syntheses or guidelines pooled it.

  1. Pooled it
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  4. Pooled it
  5. Article
  6. Review
  7. Article
  8. Article
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  11. Erythema Multiforme and COVID-19: What Do We Know?Medicina (Kaunas, Lithuania) · 2021
    Review
  12. Review
  13. Article
  14. Review
  15. COVID-19 and dermatologyTurkish journal of medical sciences · 2020
    Review
  16. Review
  17. Review
  18. Article
  19. Article
  20. A clinicopathological study of eight patients with COVID-19 pneumonia and a late-onset exanthema.Journal of the European Academy of Dermatology and Venereology : JEADV · 2020
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors.

Robert A SchwartzRutgers New Jersey Medical School, Newark, New Jersey, USA.ORCID 0000-0003-3036-3825
Camila K JannigerRutgers New Jersey Medical School, Newark, New Jersey, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

A severe cutaneous drug reaction resembling acute generalized exanthematous pustulosis resulting from ingestion of hydroxychloroquine has been documented. It is distinguishable by its longer incubation period, more varied morphology with initially urticarial and later targetoid and arcuate plaques, recalcitrance to therapy and longer duration. Given the anticipated surge in the use of hydroxychloroquine due to its reported benefits in those with coronavirus disease 2019, specific recognition of this entity is pivotal. We delineate it as generalized pustular figurate erythema.

Indexed as

Acute Generalized Exanthematous PustulosisAdrenal Cortex HormonesCoronavirus InfectionsCOVID-19Drug Hypersensitivity SyndromeFemaleFollow-Up StudiesHumansHydroxychloroquineMalePandemicsPneumonia, ViralRisk AssessmentSeverity of Illness IndexAdrenal Cortex HormonesHydroxychloroquineacute generalized exanthematous pustulosiscoronavirusCOVID-19DRESS syndromedrug rasherythema multiformefigurate erythemahydroxychloroquineSARS-2SARS-CoV-2Stevens-Johnson syndromeSweet syndrometoxic epidermal necrolysisurticaria

Identifiers

PMID32253799
PMCPMC7235477

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.