ArticleJournal of endocrinological investigation2020
Primary hyperparathyroidism and pancreatitis.
Article in Journal of endocrinological investigation, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 25 citations in OpenAlex.
- Recurrent Acute Pancreatitis Secondary to Untreated Hyperparathyroidism: A Case Report and Literature Review.Cureus · 2026Article
- Primary hyperparathyroidism-associated pancreatitis: poor prognosis, distinct serum calcium trajectories, and proactive therapeutic implications.Gastroenterology report · 2026Article
- Recurrent acute necrotizing pancreatitis secondary to hypercalcemic crisis in hyperparathyroidism: a case report.Journal of medical case reports · 2025Article
- Recurrent acute pancreatitis as an initial presentation of primary hyperparathyroidism in juvenile patient.World journal of clinical cases · 2025Article
- Importance of understanding a diagnostic-treatment algorithm for primary hyperparathyroidism-induced acute pancreatitis during pregnancy.World journal of gastroenterology · 2025Article
- Primary Hyperparathyroidism: An Analysis Amid the Co-Occurrence of Type 2 Diabetes Mellitus.Life (Basel, Switzerland) · 2025Review
- An Analysis of Primary Hyperparathyroidism in Individuals Diagnosed with Multiple Endocrine Neoplasia Type 2.Diseases (Basel, Switzerland) · 2025Review
- Acute pancreatitis and refractory hypercalcemia in the third trimester caused by parathyroid carcinoma.BMC pregnancy and childbirth · 2024Article
- Turning Points in Cross-Disciplinary Perspective of Primary Hyperparathyroidism and Pancreas Involvements: Hypercalcemia-Induced Pancreatitis,International journal of molecular sciences · 2024Review
- The value of CT-based radiomics in predicting the prognosis of acute pancreatitis.Frontiers in medicine · 2023Article
- Changes in vitamin D and calcium-phosphorus metabolism in patients with severe acute pancreatitis.Turkish journal of surgery · 2022Article
- Primary hyperparathyroidism presenting as acute pancreatitis: An institutional experience with review of the literature.World journal of gastrointestinal pharmacology and therapeutics · 2022Article
- Cardiac structural and functional abnormalities in primary hyperparathyroidism.Journal of endocrinological investigation · 2022Article
- Baseline renal dysfunction determines mortality following parathyroidectomy in primary hyperparathyroidism: analysis of Indian PHPT registry.Journal of bone and mineral metabolism · 2022Article
- Common calcium-sensing receptor (CASR) gene variants do not modify risk for chronic pancreatitis in a Hungarian cohort.Pancreatology : official journal of the International Association of Pancreatology (IAP) ... [et al.] · 2021Article
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Authors and funding
8 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe true association between primary hyperparathyroidism (PHPT) and pancreatitis continues to be controversial. In this study, we present clinical data, investigative profile, management and follow-up of PHPT patients with pancreatitis and compare this group with PHPT patients without pancreatitis.
methodsRecords of 242 patients with PHPT managed at our center over 24 years were retrospectively analyzed for demographic and laboratory data. The diagnosis of pancreatitis was entertained in the presence of at least two of the three following features: abdominal pain, levels of serum amylase greater than three times the normal or characteristic features at imaging.
resultsFifteen (6.19%) of the 242 consecutive patients with PHPT had had pancreatitis. Fourteen patients (93.3%) had acute pancreatitis (AP), while one patient had chronic calcific pancreatitis. Over half (8 of 14) of the patients with AP had at least two episodes of pancreatitis. Pancreatitis was the presenting symptom in 14 (93.3%) patients. None of the pancreatitis cases had additional risk factors for pancreatitis. PHPT patients with pancreatitis had significantly higher serum calcium and ALP than PHPT patients without pancreatitis. After successful parathyroidectomy, 14 patients had no further attacks of pancreatitis during a median follow-up of 16 months (range 2-41 months), while recurrence of pancreatitis was seen in one patient.
conclusionsWe conclude that pancreatitis can be the only presenting complaint of PHPT. Our study highlights the importance of fully investigating for PHPT in any pancreatitis patient with high normal or raised serum calcium level, especially in the absence of other common causes of pancreatitis.
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