Evidence map›Paper›PMID 32253704›Full record

ArticleMolecular biology reports2020

Ontogenetic and tissue-specific expression of gonadotropin-inhibitory hormone (GnIH) and its receptors in Catla catla.

Pravesh Kumar, K S Wisdom, Gulshan Kumar, Pathakota Gireesh-Babu, Sunil Kumar Nayak, N S Nagpure, Rupam Sharma

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Article in Molecular biology reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
1.0field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 8 citations in OpenAlex.

  1. Variation in Hypothalamic GnIH Expression and Its Association withAnimals : an open access journal from MDPI · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Pravesh KumarDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
K S WisdomDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
Gulshan KumarDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
Pathakota Gireesh-BabuDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
Sunil Kumar NayakDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
N S NagpureDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India.
Rupam SharmaDivision of Fish Genetics and Biotechnology, ICAR-Central Institute of Fisheries Education, Versova, Mumbai, 400061, India. rupams@cife.edu.in.
Central Institute of Fisheries Education · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gonadotropin-inhibitory hormone (GnIH) is an RFamide peptide, and its role in reproduction is well studied from fish to mammals, but very few reports are available about the function of GnIH during larval development. In this study, we examined the GnIH and GnIH receptors (GnIHRs) expression from embryogenesis to adult stage and tissue-specific expression in adult Catla catla using quantitative real-time (qRT) PCR. The qRT PCR analysis of GnIH mRNA during ontogenetic development showed the increasing trend from early developmental stages to the adult stage with the highest expression in 24 months fish. However, the expression of two GnIH receptors, GnIHR1 and GnIHR2 also increased from larval stages to the adults with a peak at 17 days post-hatching, while GnIHR3 showed the higher mRNA expression during embryogenesis and then decreasing gradually. Tissue distribution analysis of GnIH showed the highest mRNA expression of GnIH in the brain, followed by gonads of both the sexes. GnIHR1 and GnIHR2 were also highly expressed in the brain and gonads of both the sexes, while GnIHR3 showed the highest expression in gonads of both the sexes without any expression in the brain. These results suggest that the brain is the primary site of action for GnIH, GnIHR1 and GnIHR2, while gonads for GnIHR3.

Indexed as

AnimalsCarpsCyprinidaeFemaleGene ExpressionGene Expression Regulation, DevelopmentalGlycoproteinsGonadotropinsHypothalamic HormonesLarvaMaleNeuropeptidesReceptors, GonadotropinZebrafish ProteinsGlycoproteinsgonadotropin inhibitorGonadotropinsHypothalamic HormonesNeuropeptidesnpvf protein, zebrafishReceptors, GonadotropinRFamide peptideZebrafish ProteinsCatla catlaGene expressionGnIHOntogenyTissue-distribution

Identifiers

PMID32253704
OpenAlexW3014395331

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.