Evidence map›Paper›PMID 32253630›Full record

Observational studyJournal of medical toxicology : official journal of the American College of Medical Toxicology2020

Understanding Naloxone Uptake from an Emergency Department Distribution Program Using a Low-Energy Bluetooth Real-time Location System.

Jeffrey T Lai, Brittany P Chapman, Stephanie P Carreiro, Kavita M Babu, Edward W Boyer, Peter R Chai

Abstract readObservational Study
In one paragraph

Observational study in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. Naloxone distribution programs in the emergency department: A scoping review of the literature.Journal of the American College of Emergency Physicians open · 2024
    Article
  4. Article
  5. Prescribing Naloxone to High-Risk Patients in the Emergency Department: Is it Enough?Joint Commission journal on quality and patient safety · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jeffrey T LaiDivision of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, 55 Lake Ave North LA-218, Worcester, MA, 01655, USA. jeffrey.lai@umassmemorial.org.
Brittany P ChapmanDivision of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, 55 Lake Ave North LA-218, Worcester, MA, 01655, USA.
Stephanie P CarreiroDivision of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, 55 Lake Ave North LA-218, Worcester, MA, 01655, USA.
Kavita M BabuDivision of Medical Toxicology, Department of Emergency Medicine, University of Massachusetts Medical School, 55 Lake Ave North LA-218, Worcester, MA, 01655, USA.
Edward W BoyerDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Peter R ChaiDivision of Medical Toxicology, Department of Emergency Medicine, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.

Funding

University of Massachusetts Center for Clinical and Translational ScienceKL2TR001455 · NCATS · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI KIEFE, CATARINA I. · 2015 to 2024
$5.0M
Mentoring in Advanced mHealth Technologies and Machine Learning for HIV/Drug Abuse ResearchK24DA037109 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI BOYER, EDWARD W · 2014 to 2025
$1.9M
Development of Ingestible Biosensors to Enhance PrEP Adherence in Substance UsersK23DA044874 · NIDA · BRIGHAM AND WOMEN'S HOSPITAL · PI CHAI, PETER R · 2018 to 2022
$1.0M
iTransform: Wearable Biosensors to Detect the Evolution of Opioid Tolerance in Opioid Naïve IndividualsK23DA045242 · NIDA · UNIV OF MASSACHUSETTS MED SCH WORCESTER · PI CARREIRO, STEPHANIE P · 2019 to 2021
$566k
NIDA National Early Warning System Network (iN3): An Innovative ApproachR56DA038366 · NIDA · WRIGHT STATE UNIVERSITY · PI BOYER, EDWARD W, CARLSON, ROBERT GEOFFREY · 2014 to 2014
$300k
NCATS NIH HHS KL2 TR001455NIDA NIH HHS K23 DA044874NIDA NIH HHS K23 DA045242NIDA NIH HHS K24 DA037109NIDA NIH HHS L30 DA038357NIDA NIH HHS R56 DA038366NIH HHS K23 DA044874NIH HHS K24 5K24DA037109NIH HHS KL2 TR001455-01
6 · The paper itself

Abstract

introductionEmergency department (ED)-based naloxone distribution programs are a widespread harm reduction strategy. However, data describing the community penetrance of naloxone distributed from these programs are lacking. This study gauges acceptance of naloxone use and monitoring technology among people who use drugs (PWUD), and explores the use of real-time location systems (RTLS) in monitoring naloxone movements.

methodsA prospective observational study was conducted on a convenience sample of individuals (N = 30) presenting to a tertiary-care academic medical center ED for an opioid-related complaint. A naloxone kit equipped with a low-energy Bluetooth (BLE) tracking system was employed to detect movement of naloxone off the hospital campus as a proxy for community penetrance, followed by a qualitative interview to gauge participant acceptance of naloxone use and monitoring technology.

resultsDetection of BLE signals verified transit of 24 distributed naloxone kits off our hospital campus. Three participants whose BLE signals were not captured reported taking their kits with them following discharge, suggesting technological errors occurred; another three participants were lost to follow-up. Qualitative interviews demonstrated that participants accepted ED-based naloxone distribution programs and passive tracking technologies, but revealed concerns regarding hypothetical continuous monitoring systems and problematic interactions with first responders and law enforcement personnel.

conclusionsBased on acquired BLE signals, 80% of dispensed naloxone kits left the hospital campus. Use of RTLS to passively geolocate naloxone rescue kits is feasible, but detection can be adversely affected by technological errors. PWUD are amenable to transient monitoring technologies but identified barriers to implementation.

Indexed as

Emergency Service, HospitalGeographic Information SystemsOpioid EpidemicWireless TechnologyAdultDrug OverdoseFemaleHarm ReductionHumansMaleNaloxoneNarcotic AntagonistsOpioid-Related DisordersPatient Acceptance of Health CareProgram EvaluationProspective StudiesNaloxoneNarcotic AntagonistsDigital healthHarm reductionNaloxoneOpioidsTechnology

Identifiers

PMID32253630
PMCPMC7554286

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.