Evidence map›Paper›PMID 32253562›Full record

ArticleSurgical endoscopy2020

MIEO: a micro-invasive endoscopic operation port system for transluminal interventions-an acute and survival porcine study.

D Wilhelm, T Vogel, A Jell, S Brunner, M Kranzfelder, N Wantia, H Feussner, D Ostler, S Koller

Open access · hybridAbstract read
In one paragraph

Article in Surgical endoscopy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

D WilhelmTechnische Universität München, Fakultät für Medizin, Klinik Und Poliklinik für Chirurgie, Klinikum Rechts Der Isar, Ismaningerstr. 22, München, 81675, Germany. dirk.wilhelm@tum.de.
T VogelTechnische Universität München, Fakultät für Medizin, Klinik Und Poliklinik für Chirurgie, Klinikum Rechts Der Isar, Ismaningerstr. 22, München, 81675, Germany.
A JellTechnische Universität München, Fakultät für Medizin, Klinik Und Poliklinik für Chirurgie, Klinikum Rechts Der Isar, Ismaningerstr. 22, München, 81675, Germany.
S BrunnerArbeitsgruppe für Minimal-Invasive Technologie Und Intervention, Klinikum Rechts Der Isar, München, Germany.
M KranzfelderTechnische Universität München, Fakultät für Medizin, Klinik Und Poliklinik für Chirurgie, Klinikum Rechts Der Isar, Ismaningerstr. 22, München, 81675, Germany.
N WantiaTechnische Universität München, Institut für Virologie Und Bakteriologie, Klinikum Rechts Der Isar, München, Germany.
H FeussnerTechnische Universität München, Fakultät für Medizin, Klinik Und Poliklinik für Chirurgie, Klinikum Rechts Der Isar, Ismaningerstr. 22, München, 81675, Germany.
D OstlerArbeitsgruppe für Minimal-Invasive Technologie Und Intervention, Klinikum Rechts Der Isar, München, Germany.
S KollerRöchling Medical Waldachtal AG, Waldachtal, Deutschland, Germany.
Klinikum rechts der Isar · DETechnical University of Munich · DEWala Heilmittel (Germany) · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA reliable and sterile access through the intestinal wall to ease flexible endoscopic transluminal interventions is still appealing but lacks a suitable port system.

methodsIn a granted industry cooperation, we developed the MIEO-Port, a flexible three components overtube system that provides a temporary hermetic sealing of the intestinal wall to allow endoscopic disinfection and manipulation to gain access to the abdominal cavity. The port features an innovative head part which allows for coupling the port to the intestinal wall by vacuum suction and for controlled jetting the isolated intestinal surface with a disinfectant. The device was tested in vivo in 6 pigs for acute and long-term usability. All animal tests were approved by the local ethics committee.

resultsIn the acute experiment, the port system supported sealed endoscopic mucosa resection and transluminal cholecystectomy. In the survival study on 5 animals, the MIEO-Port proved its reliability after transcolonic peritoneoscopy. In one animal, a port dislocation occurred after extensive retroperitoneal preparation, one animal revealed bacterial contamination at necropsy; however, all animals showed a favourable course over ten days and offered no signs of peritonitis or abscedation during post-mortem examination. DISCUSSION: To the best of our knowledge, the MIEO-Port system is the first device to provide a reliable and sterile flexible access to the peritoneal cavity that can be used throughout the entire gastrointestinal tract regardless of the access route and which combines hermetic sealing with local sterilization. Further studies are warranted.

Indexed as

AnimalsCholecystectomyEndoscopic Mucosal ResectionIntestinal MucosaLaparoscopyModels, AnimalPeritoneal CavityPeritonitisSurgical InstrumentsSwineInfectionNOTESOvertubeSealingSterilizationTransluminal surgery

Identifiers

PMID32253562
PMCPMC7214494
OpenAlexW3015098782

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.