Evidence map›Paper›PMID 32253486›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2020

Effect of machine learning re-sampling techniques for imbalanced datasets in

Chenyi Xie, Richard Du, Joshua Wk Ho, Herbert H Pang, Keith Wh Chiu, Elaine Yp Lee, Varut Vardhanabhuti

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In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 51 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
51citing papers in PubMed, 3 pooled it
6.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

51 citing papers in PubMed, 3 syntheses or guidelines pooled it, 92 citations in OpenAlex.

  1. Pooled it
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  11. Clinician-driven automated data preprocessing in nuclear medicine AI environments.European journal of nuclear medicine and molecular imaging · 2025
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  13. Review
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  15. Article
  16. Artificial Intelligence in Head and Neck Surgery.Otolaryngologic clinics of North America · 2024
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Chenyi XieDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.
Richard DuDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-2062-1109
Joshua Wk HoSchool of Biomedical Science, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.ORCID https://orcid.org/0000-0003-2331-7011
Herbert H PangSchool of Public Health, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-7896-6716
Keith Wh ChiuDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-7930-1193
Elaine Yp LeeDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China.ORCID https://orcid.org/0000-0002-0627-5297
Varut VardhanabhutiDepartment of Diagnostic Radiology, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Queen Mary Hospital, Hong Kong SAR, China. varv@hku.hk.ORCID https://orcid.org/0000-0001-6677-3194
Queen Mary Hospital · CNChinese University of Hong Kong · HKUniversity of Hong Kong · HK

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeBiomedical data frequently contain imbalance characteristics which make achieving good predictive performance with data-driven machine learning approaches a challenging task. In this study, we investigated the impact of re-sampling techniques for imbalanced datasets in PET radiomics-based prognostication model in head and neck (HNC) cancer patients.

methodsRadiomics analysis was performed in two cohorts of patients, including 166 patients newly diagnosed with nasopharyngeal carcinoma (NPC) in our centre and 182 HNC patients from open database. Conventional PET parameters and robust radiomics features were extracted for correlation analysis of the overall survival (OS) and disease progression-free survival (DFS). We investigated a cross-combination of 10 re-sampling methods (oversampling, undersampling, and hybrid sampling) with 4 machine learning classifiers for survival prediction. Diagnostic performance was assessed in hold-out test sets. Statistical differences were analysed using Monte Carlo cross-validations by post hoc Nemenyi analysis.

resultsOversampling techniques like ADASYN and SMOTE could improve prediction performance in terms of G-mean and F-measures in minority class, without significant loss of F-measures in majority class. We identified optimal PET radiomics-based prediction model of OS (AUC of 0.82, G-mean of 0.77) for our NPC cohort. Similar findings that oversampling techniques improved the prediction performance were seen when this was tested on an external dataset indicating generalisability.

conclusionOur study showed a significant positive impact on the prediction performance in imbalanced datasets by applying re-sampling techniques. We have created an open-source solution for automated calculations and comparisons of multiple re-sampling techniques and machine learning classifiers for easy replication in future studies.

Indexed as

Fluorodeoxyglucose F18Head and Neck NeoplasmsCohort StudiesHumansMachine LearningProgression-Free SurvivalFluorodeoxyglucose F1818F-FDG PETHead and neck cancerImbalanced datasetsRadiomicsRe-sampling techniques

Identifiers

PMID32253486
OpenAlexW3014904955

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.