Evidence map›Paper›PMID 32253462›Full record

ReviewCellular and molecular life sciences : CMLS2020

Mechanisms of larynx and vocal fold development and pathogenesis.

Vlasta Lungova, Susan L Thibeault

Open access · greenAbstract readReview
In one paragraph

Review in Cellular and molecular life sciences : CMLS, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.8field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Case Report: Laryngeal web in a Yorkshire Terrier.Frontiers in veterinary science · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. The domestication of the larynx: The neural crest connection.Journal of experimental zoology. Part B, Molecular and developmental evolution · 2024
    Article
  12. Article
  13. Assessment of Preoperative Predictors for Difficult Laryngeal Exposure in Endolaryngeal Surgery.Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India · 2024
    Article
  14. Article
  15. Article
  16. Review
  17. Article
  18. Article
  19. Article
  20. Transcriptome Dynamics in the Developing Larynx, Trachea, and Esophagus.Frontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Vlasta LungovaDepartment of Surgery, University of Wisconsin Madison, 5103 WIMR, 1111 Highland Ave, Madison, WI, 53705, USA.
Susan L ThibeaultDepartment of Surgery, University of Wisconsin Madison, 5103 WIMR, 1111 Highland Ave, Madison, WI, 53705, USA. thibeault@surgery.wisc.edu.
University of Wisconsin–Madison · US

Funding

Engineering the Vocal Fold MucosaR01DC004336 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI Susan Lynn Thibeault · 2000 to 2026
$14.6M
Mechanisms of innate immune-microbial interactions in vocal fold InflammationR01DC012773 · NIDCD · UNIVERSITY OF WISCONSIN-MADISON · PI THIBEAULT, SUSAN LYNN · 2013 to 2022
$4.5M
NIDCD NIH HHS DC12773NIDCD NIH HHS DC4336NIDCD NIH HHS R01 DC004336NIDCD NIH HHS R01 DC012773
6 · The paper itself

Abstract

The larynx and vocal folds sit at the crossroad between digestive and respiratory tracts and fulfill multiple functions related to breathing, protection and phonation. They develop at the head and trunk interface through a sequence of morphogenetic events that require precise temporo-spatial coordination. We are beginning to understand some of the molecular and cellular mechanisms that underlie critical processes such as specification of the laryngeal field, epithelial lamina formation and recanalization as well as the development and differentiation of mesenchymal cell populations. Nevertheless, many gaps remain in our knowledge, the filling of which is essential for understanding congenital laryngeal disorders and the evaluation and treatment approaches in human patients. This review highlights recent advances in our understanding of the laryngeal embryogenesis. Proposed genes and signaling pathways that are critical for the laryngeal development have a potential to be harnessed in the field of regenerative medicine.

Indexed as

AnimalsCell DifferentiationHumansLaryngeal DiseasesLarynxMesenchymal Stem CellsSignal TransductionSOXB1 Transcription FactorsThyroid Nuclear Factor 1Vocal CordsSOXB1 Transcription FactorsThyroid Nuclear Factor 1CongenitalEmbryologyLaryngealVocal cords

Identifiers

PMID32253462
PMCPMC7511430
OpenAlexW3014360764

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.