Evidence map›Paper›PMID 32253455›Full record

ArticleNeuroradiology2020

Cortical presentation of language functions in patients after total laryngectomy: a fMRI study.

Aleksandra Wypych, Małgorzata Wierzchowska, Paweł Burduk, Elżbieta Zawada, Katarzyna Nadolska, Zbigniew Serafin

Open access · hybridAbstract read
In one paragraph

Article in Neuroradiology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 51% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Aleksandra WypychThe Interdisciplinary Center for Modern Technologies, Nicolaus Copernicus University, Toruń, Poland.
Małgorzata WierzchowskaDepartment of Otolaryngology, Oncology and Oral and Maxillofacial Surgery, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Paweł BurdukDepartment of Otolaryngology, Oncology and Oral and Maxillofacial Surgery, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Elżbieta ZawadaDepartment of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Katarzyna NadolskaDepartment of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland.
Zbigniew SerafinDepartment of Radiology and Diagnostic Imaging, Nicolaus Copernicus University, Collegium Medicum, Bydgoszcz, Poland. serafin@cm.umk.pl.
Nicolaus Copernicus University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThe aim of this study is to use functional magnetic resonance (fMRI) to analyse the cortical presentation of selected language functions in patients after a total laryngectomy.

methodsEighteen patients after total laryngectomy treated with electrolarynx speech and 18 volunteers were included. The mean number of patients' post-operative speech rehabilitation sessions was five (range of 3-8 sessions). Four paradigms were used, including noun generation, pseudoword reading, reading phrases with pseudowords, and nonliteral sign reproduction.

resultsIn noun, the most significant difference between the groups was the stronger activation of both lingual gyri in the volunteers. Pseudoword reading resulted in stronger activations in patients than in volunteers in the lingual gyri, the right cerebellum, the right Broca's area, and the right parietal operculum. Reading phrases with pseudowords involved different parts of the Brodmann area 40. During nonliteral sign reproduction, there was a stronger activation of the left Broca's area in volunteers and a stronger activation of the left premotor cortex in patients.

conclusionThis study provides evidence of altered cortical activation in response to language tasks in patients after a laryngectomy compared with healthy volunteers, which may be considered brain plasticity in response to a laryngectomy.

Indexed as

LaryngectomyNeuronal PlasticitySpeech Production MeasurementBrainFemaleHumansLarynx, ArtificialMagnetic Resonance ImagingMaleMiddle AgedPsycholinguisticsGray matterLaryngectomyMagnetic resonance imaging

Identifiers

PMID32253455
PMCPMC7311494
OpenAlexW3014936371

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.