Evidence map›Paper›PMID 32253451›Full record

ReviewDer Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete2020

[Autoinflammatory skin diseases : Diagnosis and therapy].

J Ehrchen, C Drerup

Abstract readReview
PubMed Publisher
In one paragraph

Review in Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.3field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 4 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

J EhrchenKlinik für Hautkrankheiten - Allgemeine Dermatologie und Venerologie -, Universitätsklinikum Münster, Von-Esmarch Str. 58, 48149, Münster, Deutschland. jan.ehrchen@ukmuenster.de.
C DrerupKlinik für Hautkrankheiten - Allgemeine Dermatologie und Venerologie -, Universitätsklinikum Münster, Von-Esmarch Str. 58, 48149, Münster, Deutschland.
Klinik und Poliklinik für Hautkrankheiten · DEUniversity Hospital Münster · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Autoinflammatory syndromes are characterized by an exaggerated activation of the innate immune system and frequently present with skin symptoms. In contrast to autoimmune disorders no specific autoantibodies or autoreactive immune cells are detected. Thus, the diagnosis is usually difficult and can only be made by a careful interpretation of anamnestic, clinical and laboratory parameters. In some hereditary autoimmune syndromes specific genetic mutations are described and can be helpful for the diagnosis. For treatment of these disorders both classic immunomodulatory drugs and specific cytokine inhibitors are used, mainly directed against interleukin‑1. Long-term therapy is generally required.

Indexed as

Hereditary Autoinflammatory DiseasesAutoimmune DiseasesCytokinesHidradenitis SuppurativaHumansInterleukin-1Pyoderma GangrenosumSkin DiseasesSyndromeCytokinesInterleukin-1Autoinflammatory syndromesHidradenitis suppurativaInterleukin‑1Neutrophilic urticarial dermatosisPyoderma gangrenosum

Identifiers

PMID32253451
OpenAlexW3014646335

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.