Evidence map›Paper›PMID 32253428›Full record

ReviewJournal of biomechanical engineering2020

Nonlinear Elastic and Inelastic Properties of Cells.

Wonyeong Jung, Jing Li, Ovijit Chaudhuri, Taeyoon Kim

Open access · greenAbstract readReview
In one paragraph

Review in Journal of biomechanical engineering, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.3field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 25 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Cell-extracellular matrix mechanotransduction in 3D.Nature reviews. Molecular cell biology · 2023
    Review
  5. Review
  6. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Wonyeong JungWeldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN 47907.
Jing LiWeldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN 47907.
Ovijit ChaudhuriDepartment of Mechanical Engineering, Stanford University, 440 Escondido Mall, Stanford, CA 94305.
Taeyoon KimWeldon School of Biomedical Engineering, Purdue University, 206 S. Martin Jischke Drive, West Lafayette, IN 47907.
Purdue University West Lafayette · USStanford University · US

Funding

Universal Roles of Force Generation and Transmission in Biological SystemsR01GM126256 · NIGMS · PURDUE UNIVERSITY · PI KIM, TAEYOON · 2017 to 2021
$2.3M
NIGMS NIH HHS R01 GM126256
6 · The paper itself

Abstract

Mechanical forces play an important role in various physiological processes, such as morphogenesis, cytokinesis, and migration. Thus, in order to illuminate mechanisms underlying these physiological processes, it is crucial to understand how cells deform and respond to external mechanical stimuli. During recent decades, the mechanical properties of cells have been studied extensively using diverse measurement techniques. A number of experimental studies have shown that cells are far from linear elastic materials. Cells exhibit a wide variety of nonlinear elastic and inelastic properties. Such complicated properties of cells are known to emerge from unique mechanical characteristics of cellular components. In this review, we introduce major cellular components that largely govern cell mechanical properties and provide brief explanations of several experimental techniques used for rheological measurements of cell mechanics. Then, we discuss the representative nonlinear elastic and inelastic properties of cells. Finally, continuum and discrete computational models of cell mechanics, which model both nonlinear elastic and inelastic properties of cells, will be described.

Indexed as

ElasticityModels, BiologicalNonlinear DynamicsAnimalsBiomechanical PhenomenaHumansRheologyStress, Mechanicalcell mechanicscytoskeletoninelasticnonlinear elasticviscoelasticity

Identifiers

PMID32253428
PMCPMC7477719
OpenAlexW3015052410

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.