Evidence map›Paper›PMID 32253237›Full record

ArticleDevelopment (Cambridge, England)2020

Cleft lip and cleft palate in

SungKyoung Lee, Matthew J Sears, Zijun Zhang, Hong Li, Imad Salhab, Philippe Krebs, Yi Xing, Hyun-Duck Nah, Trevor Williams, Russ P Carstens

Abstract read
In one paragraph

Article in Development (Cambridge, England), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 28 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
28citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

28 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Review
  7. Review
  8. Article
  9. Article
  10. Article
  11. Functional analysis ofbioRxiv : the preprint server for biology · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Alternative splicing in shaping the molecular landscape of the cochlea.Frontiers in cell and developmental biology · 2023
    Review
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

SungKyoung LeeDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA russcars@upenn.edu.
Matthew J SearsDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA.
Zijun ZhangCenter for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Hong LiDepartment of Craniofacial Biology, University of Colorado School of Dental, Medicine, Aurora, CO 80045, USA.
Imad SalhabDivision of Plastic and Reconstructive Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Philippe KrebsInstitute of Pathology, University of Bern, Bern, Switzerland.
Yi XingCenter for Computational and Genomic Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Hyun-Duck NahDivision of Plastic and Reconstructive Surgery, The Children's Hospital of Philadelphia, Philadelphia, PA 19104, USA.
Trevor WilliamsDepartment of Craniofacial Biology, University of Colorado School of Dental, Medicine, Aurora, CO 80045, USA.
Russ P CarstensDepartment of Medicine, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA 19104, USA russcars@upenn.edu.ORCID 0000-0002-8083-0412

Funding

UNIVERSITY OF PENNSYLVANIA CAN CTR SUPPORT GRANTP30CA016520 · NCI · UNIVERSITY OF PENNSYLVANIA · PI SHELLEY L BERGER · 1985 to 2026
$222.3M
VIRAL VECTOR COREP30DK019525 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI MITCHELL A. LAZAR · 1986 to 2026
$48.3M
TRANSGENIC AND CHIMERIC MOUSE COREP30DK050306 · NIDDK · UNIVERSITY OF PENNSYLVANIA · PI Ken Hashigiwa Cadwell · 1997 to 2026
$32.5M
The Role of Hyaluronic Acid Receptors in Tendon HealingP30AR050950 · NIAMS · UNIVERSITY OF PENNSYLVANIA · PI PIGNOLO, ROBERT JOHN · 2006 to 2015
$6.2M
Roles of Epithelial Splicing Regulatory Proteins in craniofacial developmentR01DE024749 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI CARSTENS, RUSS PAUL · 2015 to 2019
$2.9M
RNA dynamics in the developing mouse faceU01DE024429 · NIDCR · UNIVERSITY OF COLORADO DENVER · PI HOOPER, JOAN E, JONES, KENNETH LLOYD · 2014 to 2018
$1.7M
Roles of Epithelial Splicing Regulatory Proteins in craniofacial developmentR56DE024749 · NIDCR · UNIVERSITY OF PENNSYLVANIA · PI CARSTENS, RUSS PAUL · 2014 to 2014
$462k
NCI NIH HHS P30 CA016520NIAMS NIH HHS P30 AR050950NIDCR NIH HHS R01 DE024749NIDCR NIH HHS R56 DE024749NIDCR NIH HHS U01 DE024429NIDDK NIH HHS P30 DK019525NIDDK NIH HHS P30 DK050306
6 · The paper itself

Abstract

Cleft lip is one of the most common human birth defects. However, there remain a limited number of mouse models of cleft lip that can be leveraged to characterize the genes and mechanisms that cause this disorder. Crosstalk between epithelial and mesenchymal cells underlies formation of the face and palate, but the basic molecular events mediating this crosstalk remain poorly understood. We previously demonstrated that mice lacking the epithelial-specific splicing factor

Indexed as

Signal TransductionAlternative SplicingAnimalsCell ProliferationCleft LipCleft PalateEctodermEmbryo, MammalianEpitheliumFaceGene Expression Regulation, DevelopmentalGenes, ReporterMesodermMice, KnockoutOrganogenesisPalateESRP1 protein, mouseRNA-Binding ProteinsCleft lipCleft palateEpithelial-mesenchymal crosstalkLip morphogenesis

Identifiers

PMID32253237
PMCPMC7225129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.