Evidence map›Paper›PMID 32253215›Full record

ArticleAntimicrobial agents and chemotherapy2020

Transferable Resistance Gene

Lara M Almeida, François Lebreton, Anthony Gaca, Paulo M Bispo, Jose T Saavedra, Rodrigo N Calumby, Luciano M Grillo, Ticiano G Nascimento, Pedro H Filsner, Andrea M Moreno and 1 more

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.5field-weighted citation impact, top 23% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 32 citations in OpenAlex.

  1. Genomic Characterization of Multiple Antibiotic-ResistantAntibiotics (Basel, Switzerland) · 2025
    Article
  2. Article
  3. Review
  4. Prevalence and Associated Factors ofAntibiotics (Basel, Switzerland) · 2023
    Article
  5. Co-Existence of Oxazolidinone Resistance GenesAntibiotics (Basel, Switzerland) · 2023
    Article
  6. Detection of Genes Related to Linezolid Resistance (Advanced biomedical research · 2023
    Article
  7. Article
  8. Article
  9. Antimicrobial Susceptibility ofAntibiotics (Basel, Switzerland) · 2022
    Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Lara M AlmeidaDepartment of Clinical and Toxicological Analyses, Faculty of Pharmaceutical Sciences, University of São Paulo, SP, Brazil larameal@gmail.com.ORCID 0000-0002-9027-5221
François LebretonDepartment of Ophthalmology and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Anthony GacaDepartment of Ophthalmology and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Paulo M BispoDepartment of Ophthalmology and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Jose T SaavedraDepartment of Ophthalmology and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Rodrigo N CalumbyInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Alagoas, Brazil.
Luciano M GrilloInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Alagoas, Brazil.ORCID 0000-0001-8812-6342
Ticiano G NascimentoInstitute of Pharmaceutical Sciences, Federal University of Alagoas, Maceió, Alagoas, Brazil.ORCID 0000-0002-3856-8764
Pedro H FilsnerSchool of Veterinary Medicine and Animal Science, University of São Paulo, SP, Brazil.
Andrea M MorenoSchool of Veterinary Medicine and Animal Science, University of São Paulo, SP, Brazil.ORCID 0000-0002-3290-566X
Michael S GilmoreDepartment of Ophthalmology and Department of Microbiology and Immunobiology, Harvard Medical School, Boston, Massachusetts, USA.
Harvard University · USUniversidade de São Paulo · BRUniversidade Federal de Alagoas · BR

Funding

Technical Mother Machine CoreP01AI083214 · NIAID · SCHEPENS EYE RESEARCH INSTITUTE · PI Michael S Gilmore · 2009 to 2026
$39.4M
NIAID NIH HHS P01 AI083214
6 · The paper itself

Abstract

OptrA is an ATP-binding cassette (ABC)-F protein that confers resistance to oxazolidinones and phenicols and can be either plasmid-encoded or chromosomally encoded. Here, we isolated 13

Indexed as

Enterococcus faecalisOxazolidinonesAnimalsAnti-Bacterial AgentsBrazilDrug Resistance, BacterialGenes, BacterialSwineAnti-Bacterial AgentsOxazolidinonesEnterococcus faecalisoptrAoxazolidinonesTn554

Identifiers

PMID32253215
PMCPMC7269498
OpenAlexW3015061147

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.