Evidence map›Paper›PMID 32253213›Full record

ArticleAntimicrobial agents and chemotherapy2020

Novel Peptide from Commensal Staphylococcus simulans Blocks Methicillin-Resistant Staphylococcus aureus Quorum Sensing and Protects Host Skin from Damage.

Morgan M Brown, Jakub M Kwiecinski, Luis Mejia Cruz, Ali Shahbandi, Daniel A Todd, Nadja B Cech, Alexander R Horswill

Open access · greenAbstract read
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
1.2field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 75 citations in OpenAlex.

  1. Trial
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Interaction BetweenCurrent pharmaceutical biotechnology · 2026
    Review
  8. Establishing anmSphere · 2025
    Article
  9. Review
  10. Toward the Next Generation of In Silico Modeling of Dynamic Host-Microbiota Interactions in the Skin.JID innovations : skin science from molecules to population health · 2025
    Review
  11. Article
  12. Article
  13. Article
  14. DisarmingPathogens (Basel, Switzerland) · 2025
    Review
  15. Article
  16. Microbe Interactions within the Skin Microbiome.Antibiotics (Basel, Switzerland) · 2024
    Review
  17. Review
  18. bioRxiv : the preprint server for biology · 2023
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Morgan M BrownDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Jakub M KwiecinskiDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA.
Luis Mejia CruzDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Ali ShahbandiDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Daniel A ToddDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Nadja B CechDepartment of Chemistry and Biochemistry, University of North Carolina at Greensboro, Greensboro, North Carolina, USA.
Alexander R HorswillDepartment of Immunology and Microbiology, University of Colorado School of Medicine, Aurora, Colorado, USA alexander.horswill@cuanschutz.edu.ORCID 0000-0002-5568-0096
University of North Carolina at Greensboro · USUniversity of Colorado Denver · USVA Eastern Colorado Health Care System · US

Funding

Molecular Pathogenesis of Infectious DiseasesT32AI052066 · NIAID · UNIVERSITY OF COLORADO DENVER · PI VAN DYK, LINDA F. · 2002 to 2022
$2.3M
Impact of commensal cross-talk on MRSA colonization and infectionR21AI133089 · NIAID · UNIVERSITY OF COLORADO DENVER · PI HORSWILL, ALEXANDER R · 2018 to 2019
$432k
Quorum Sensing Dependent Interactions with Biofilms and Innate Immunity DefensesI01BX002711 · VA · VA EASTERN COLORADO HEALTH CARE SYSTEM · PI ALEXANDER R HORSWILL · 2015 to 2026
–
BLRD VA I01 BX002711NIAID NIH HHS R21 AI133089NIAID NIH HHS T32 AI052066
6 · The paper itself

Abstract

Recent studies highlight the abundance of commensal

Indexed as

Methicillin-Resistant Staphylococcus aureusStaphylococcal InfectionsAnimalsBacterial ProteinsHumansMicePeptidesQuorum SensingStaphylococcusBacterial ProteinsPeptidesantimicrobial activitycolonization resistancepolymicrobial interactionsquorum sensing

Identifiers

PMID32253213
PMCPMC7269516
OpenAlexW3014639384

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.