Evidence map›Paper›PMID 32252673›Full record

ArticleBMC neurology2020

Thrombotic thrombocytopenic purpura with reversible splenial lesion syndrome: a case report.

Song Hu, Xinyue Hou, Shuhao Liu, Chunxiao Fei, Lingyan Zhou, Ang Xing, Junqing Zhang, Chunming Yong, Xiaomeng Wang

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC neurology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.2field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Can plasma exchange therapy be an option for the treatment of SARS-CoV-2 Related Splenial Lesion Syndrome: Two cases from the pediatric intensive care unit.Transfusion and apheresis science : official journal of the World Apheresis Association : official journal of the European Society for Haemapheresis · 2022
    Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Song HuThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Xinyue HouThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Shuhao LiuThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chunxiao FeiThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Lingyan ZhouThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Ang XingThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China. xingang2005@sina.com.
Junqing ZhangThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Chunming YongThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Xiaomeng WangThe Affiliated Hospital of Qingdao University, Qingdao, Shandong, China.
Qingdao University · CNAffiliated Hospital of Qingdao University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundReversible splenial lesion syndrome (RESLES) is known to cause severe psychiatric symptoms but is also a very rare clinical disease in which the specific aetiology is unknown. According to current reports, there are major causes of the disease, including viral or bacterial infection, epilepsy, anti-epileptic drug withdrawal, high-altitude cerebral oedema, and metabolic disorders such as hypoglycaemia and hypernatraemia. In this article, we report a patient with thrombotic thrombocytopenic purpura (TTP) who presented with RESLES. CASE PRESENTATION: A 34-year-old female patient who presented with fever and progression of disorder of consciousness was eventually diagnosed with RESLES based on brain imaging. Moreover, clinical features and peripheral smears demonstrating schistocytes and thrombocytopenia confirmed a diagnosis of TTP. RESLES can be improved by plasma exchange therapy.

conclusionThis rare case highlights the occurrence of RESLES as a presenting feature of the expanding list of unusual neurological manifestations of TTP.

Indexed as

AdultCentral Nervous System DiseasesCorpus CallosumFemaleHumansMagnetic Resonance ImagingNeuroimagingPlasma ExchangePurpura, Thrombotic ThrombocytopenicSyndromeHemolytic uremic syndromeReversible splenial lesion syndromeThrombotic thrombocytopenic purpura

Identifiers

PMID32252673
PMCPMC7133000
OpenAlexW3014981787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.